Nucleoside ribosyltransferase

Nucleoside ribosyltransferase
nucleoside ribosyltransferase
Identifiers
EC number 2.4.2.5
CAS number 9030-31-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a nucleoside ribosyltransferase (EC 2.4.2.5) is an enzyme that catalyzes the chemical reaction

D-ribosyl-base1 + base2 \rightleftharpoons D-ribosyl-base2 + base1

Thus, the two substrates of this enzyme are D-ribosyl-base1 and base2, whereas its two products are D-ribosyl-base2 and base1.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is nucleoside:purine(pyrimidine) D-ribosyltransferase. This enzyme is also called nucleoside N-ribosyltransferase.

References

  • KOCH AL (1956). "Some enzymes of nucleoside metabolism of Escherichia coli". J. Biol. Chem. 223 (1): 535–49. PMID 13376622.