- Desosamine
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Desosamine 
(2R,3S,5R)-3-Dimethylamino-2,5-dihydroxyhexanalIdentifiers CAS number 5779-39-5 PubChem 168997 ChemSpider 147813 
ChEBI CHEBI:32540 Jmol-3D images Image 1 - O=C[C@H](O)[C@@H](N(C)C)C[C@H](O)C
- InChI=1S/C8H17NO3/c1-6(11)4-7(9(2)3)8(12)5-10/h5-8,11-12H,4H2,1-3H3/t6-,7+,8+/m1/s1
Key: VTJCSBJRQLZNHE-CSMHCCOUSA-N
InChI=1/C8H17NO3/c1-6(11)4-7(9(2)3)8(12)5-10/h5-8,11-12H,4H2,1-3H3/t6-,7+,8+/m1/s1
Key: VTJCSBJRQLZNHE-CSMHCCOUBT
Properties Molecular formula C8H17NO3 Molar mass 175.23 g/mol 
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Desosamine is a 3-(dimethylamino)-3,4,6-trideoxyhexose found in certain macrolide antibiotics such as the commonly prescribed erythromycin.[1][2]
Biosynthesis
Six enzymes are required for its biosynthesis from TDP-glucose in Streptomyces venezuelae.[1]
References
- ^ a b Rodríguez E, Peirú S, Carney JR, Gramajo H (March 2006). "In vivo characterization of the dTDP-D-desosamine pathway of the megalomicin gene cluster from Micromonospora megalomicea". Microbiology (Reading, Engl.) 152 (Pt 3): 667–73. doi:10.1099/mic.0.28680-0. PMID 16514147.
- ^ Flickinger MC, Perlman D (April 1975). "Microbial degradation of erythromycins A and B". J. Antibiot. 28 (4): 307–11. PMID 1150530. http://www.journalarchive.jst.go.jp/jnlpdf.php?cdjournal=antibiotics1968&cdvol=28&noissue=4&startpage=307&lang=en&from=jnlabstract.
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