Dehydrocholic acid

Dehydrocholic acid
IUPAC name (4R)-4-[(5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7,12-trioxo-1,2,4,5,6,8,9,11,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
Identifiers
CAS number	81-23-2
PubChem	6674
ChemSpider	6422
KEGG	D06438
ChEMBL	CHEMBL514446
Jmol-3D images	Image 1
SMILES O=C2C[C@H]3CC(=O)[C@H]1[C@H]4[C@](C(=O)C[C@@H]1[C@@]3(C)CC2)([C@H](CC4)[C@H](C)CCC(=O)O)C
InChI InChI=1/C24H34O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-14,16-18,22H,4-12H2,1-3H3,(H,28,29)/t13-,14+,16-,17+,18+,22+,23+,24-/m1/s1 Key: OHXPGWPVLFPUSM-KLRNGDHRBE
Properties
Molecular formula	C24H34O5
Molar mass	402.52
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dehydrocholic acid is a synthetic bile acid, manufactured by the oxidation of cholic acid. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load.^[1]

References

1. ^ Yousef IM, Barnwell SG, Tuchweber B, Weber A, Roy CC (1987). "Effect of complete sulfation of bile acids on bile formation in rats". Hepatology 7 (3): 535–42. doi:10.1002/hep.1840070320. PMID 3570165.