D-4-hydroxyphenylglycine transaminase

D-4-hydroxyphenylglycine transaminase
D-4-hydroxyphenylglycine transaminase
Identifiers
EC number 2.6.1.72
CAS number 117444-05-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) is an enzyme that catalyzes the chemical reaction

D-4-hydroxyphenylglycine + 2-oxoglutarate \rightleftharpoons 4-hydroxyphenylglyoxylate + L-glutamate

Thus, the two substrates of this enzyme are D-4-hydroxyphenylglycine and 2-oxoglutarate, whereas its two products are 4-hydroxyphenylglyoxylate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase. This enzyme is also called D-hydroxyphenylglycine aminotransferase. It employs one cofactor, pyridoxal phosphate.

References

  • Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953. 
  • Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953. 
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