- N6-hydroxylysine O-acetyltransferase
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N6-hydroxylysine O-acetyltransferase Identifiers EC number 2.3.1.102 CAS number 101077-53-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a N6-hydroxylysine O-acetyltransferase (EC 2.3.1.102) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + N6-hydroxy-L-lysine
CoA + N6-acetyl-N6-hydroxy-L-lysine
Thus, the two substrates of this enzyme are acetyl-CoA and N6-hydroxy-L-lysine, whereas its two products are CoA and N6-acetyl-N6-hydroxy-L-lysine.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase. Other names in common use include N6-hydroxylysine:acetyl CoA N6-transacetylase, N6-hydroxylysine acetylase, and acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase. This enzyme participates in lysine degradation.
References
- Coy M, Paw BH, Bindereif A, Neilands JB (1986). "Isolation and properties of N epsilon-hydroxylysine:acetyl coenzyme A N epsilon-transacetylase from Escherichia coli pABN11". Biochemistry. 25 (9): 2485–9. doi:10.1021/bi00357a030. PMID 3521734.
- de Lorenzo V, Bindereif A, Paw BH, Neilands JB (1986). "Aerobactin biosynthesis and transport genes of plasmid ColV-K30 in Escherichia coli K-12". J. Bacteriol. 165 (2): 570–8. PMC 214457. PMID 2935523. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=214457.
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