Glycerol-3-phosphate O-acyltransferase
- Glycerol-3-phosphate O-acyltransferase
In enzymology, a glycerol-3-phosphate O-acyltransferase (EC number|2.3.1.15) is an enzyme that catalyzes the chemical reaction
:acyl-CoA + sn-glycerol 3-phosphate CoA + 1-acyl-sn-glycerol 3-phosphate
Thus, the two substrates of this enzyme are acyl-CoA and sn-glycerol 3-phosphate, whereas its two products are CoA and 1-acyl-sn-glycerol 3-phosphate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase. Other names in common use include alpha-glycerophosphate acyltransferase, 3-glycerophosphate acyltransferase, ACP:sn-glycerol-3-phosphate acyltransferase, glycerol 3-phosphate acyltransferase, glycerol phosphate acyltransferase, glycerol phosphate transacylase, glycerophosphate acyltransferase, glycerophosphate transacylase, sn-glycerol 3-phosphate acyltransferase, and sn-glycerol-3-phosphate acyltransferase. This enzyme participates in glycerolipid metabolism and glycerophospholipid metabolism.
tructural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1IUQ and PDB link|1K30.
References
*
*
*
*
External links
::"The CAS registry number for this enzyme class is CAS registry|9029-96-3."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
glycerol-3-phosphate O-acyltransferase — glyc·er·ol 3 phos·phate O ac·yl·trans·fer·ase (glisґər ol fosґfāt a″səl transґfər ās) [EC 2.3.1.15] an enzyme of the transferase class that catalyzes the transfer of an acyl group to glycerol 3 phosphate from an… … Medical dictionary
glycerol-3-phosphate acyltransferase — An enzyme that participates in phospholipid biosynthesis, catalyzing the transfer of an acyl group from a fatty acyl CoA to sn glycerol 3 phosphate, producing coenzyme A and lysophosphatidic acid … Medical dictionary
2-acylglycerol-3-phosphate O-acyltransferase — In enzymology, a 2 acylglycerol 3 phosphate O acyltransferase (EC number|2.3.1.52) is an enzyme that catalyzes the chemical reaction:acyl CoA + 2 acyl sn glycerol 3 phosphate ightleftharpoons CoA + 1,2 diacyl sn glycerol 3 phosphateThus, the two… … Wikipedia
1-acylglycerol-3-phosphate O-acyltransferase — In enzymology, a 1 acylglycerol 3 phosphate O acyltransferase (EC number|2.3.1.51) is an enzyme that catalyzes the chemical reaction:acyl CoA + 1 acyl sn glycerol 3 phosphate ightleftharpoons CoA + 1,2 diacyl sn glycerol 3 phosphateThus, the two… … Wikipedia
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
Carnitine palmitoyltransferase I — carnitine palmitoyltransferase 1A (liver) Identifiers Symbol CPT1A Alt. symbols CPT1 Entrez 1374 … Wikipedia
Citrate synthase — Identifiers Symbol CS Entrez 1431 HUGO … Wikipedia
Dihydrolipoyl transacetylase — dihydrolipoyllysine residue acetyltransferase Atomic structure of a single subunit of dihydrolipoyl transacetylase from Azotobacter vinelandii that makes up the structural core of the pyruvate dehydrogenase multienzyme complex.[1] … Wikipedia
ABHD5 — Abhydrolase domain containing 5 Identifiers Symbols ABHD5; CDS; CGI58; IECN2; MGC8731; NCIE2 External IDs … Wikipedia
Choline acetyltransferase — Identifiers EC number 2.3.1.6 CAS number 9012 78 6 … Wikipedia
