N-benzyloxycarbonylglycine hydrolase

N-benzyloxycarbonylglycine hydrolase
N-benzyloxycarbonylglycine hydrolase
Identifiers
EC number 3.5.1.58
CAS number 91930-69-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-benzyloxycarbonylglycine hydrolase (EC 3.5.1.58) is an enzyme that catalyzes the chemical reaction

N-benzyloxycarbonylglycine + H2O \rightleftharpoons benzyl alcohol + CO2 + glycine

Thus, the two substrates of this enzyme are N-benzyloxycarbonylglycine and H2O, whereas its 3 products are benzyl alcohol, CO2, and glycine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzyloxycarbonylglycine urethanehydrolase. Other names in common use include benzyloxycarbonylglycine hydrolase, Nalpha-carbobenzoxyamino acid amidohydrolase, Nalpha-benzyloxycarbonyl amino acid urethane hydrolase, and Nalpha-benzyloxycarbonyl amino acid urethane hydrolase I. It has 2 cofactors: zinc, and Cobalt.

References

  • characterization of a novel enzyme N (1985). "alpha-benzyloxycarbonyl amino acid urethane hydrolase, from Streptococcus faecalis R ATCC 8043". Agric. Biol. Chem. 49: 967–972.