Citrate dehydratase

citrate dehydratase
Identifiers
EC number	4.2.1.4
CAS number	9024-39-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a citrate dehydratase (EC 4.2.1.4) is an enzyme that catalyzes the chemical reaction

citrate $\rightleftharpoons$ cis-aconitate + H₂O

Hence, this enzyme has one substrate, citrate, and two products, cis-aconitate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is citrate hydro-lyase (cis-aconitate-forming). This enzyme is also called citrate hydro-lyase.

References

• NEILSON NE (1955). "The aconitase of Aspergillus niger". Biochim. Biophys. Acta. 17 (1): 139–40. doi:10.1016/0006-3002(55)90330-9. PMID 13239639. 

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