Malate-CoA ligase

Malate-CoA ligase

In enzymology, a malate-CoA ligase (EC number|6.2.1.9) is an enzyme that catalyzes the chemical reaction

:ATP + malate + CoA ightleftharpoons ADP + phosphate + malyl-CoA

The 3 substrates of this enzyme are ATP, malate, and CoA, whereas its 3 products are ADP, phosphate, and malyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is malate:CoA ligase (ADP-forming). Other names in common use include malyl-CoA synthetase, malyl coenzyme A synthetase, and malate thiokinase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37318-58-4."

Gene Ontology (GO) codes


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