Choline sulfotransferase

Choline sulfotransferase
choline sulfotransferase
Identifiers
EC number 2.8.2.6
CAS number 9047-23-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a choline sulfotransferase (EC 2.8.2.6) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + choline \rightleftharpoons adenosine 3',5'-bisphosphate + choline sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and choline, whereas its two products are adenosine 3',5'-bisphosphate and choline sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase. This enzyme participates in sulfur metabolism.

References

  • Orsi BA and Spencer B (Tokyo). "Choline sulphokinase (sulphotransferase)". J. Biochem.: 81–91. 
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