- N6-methyl-lysine oxidase
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N6-methyl-lysine oxidase Identifiers EC number 1.5.3.4 CAS number 37256-28-3 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a N6-methyl-lysine oxidase (EC 1.5.3.4) is an enzyme that catalyzes the chemical reaction
- N6-methyl-L-lysine + H2O + O2 L-lysine + formaldehyde + H2O2
The 3 substrates of this enzyme are N6-methyl-L-lysine, H2O, and O2, whereas its 3 products are L-lysine, formaldehyde, and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is N6-methyl-L-lysine:oxygen oxidoreductase (demethylating). Other names in common use include epsilon-alkyl-L-lysine:oxygen oxidoreductase, N6-methyllysine oxidase, epsilon-N-methyllysine demethylase, epsilon-alkyllysinase, and 6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating).
References
- Kim S, Benoiton L and Paik WK (1964). "alpha-Alkyllysinase. Purification and properties of the enzyme". J. Biol. Chem. 239: 3790–3796.
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