Superoxide reductase

In enzymology, a superoxide reductase (EC number|1.15.1.2) is an enzyme that catalyzes the chemical reaction

:reduced rubredoxin + superoxide + 2 H⁺ $ightleftharpoons$ rubredoxin + H₂O₂

The 3 substrates of this enzyme are reduced rubredoxin, superoxide, and H⁺, whereas its two products are rubredoxin and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on superoxide as accepto acting on superoxide as acceptor (only sub-subclass identified t date). The systematic name of this enzyme class is rubredoxin:superoxide oxidoreductase. Other names in common use include neelaredoxin, and desulfoferrodoxin.

tructural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1VZG, PDB link|1VZH, PDB link|1VZI, PDB link|1Y07, PDB link|2AMU, PDB link|2HVB, PDB link|2JI1, PDB link|2JI2, and PDB link|2JI3.

References

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External links

Gene Ontology (GO) codes