PLCG1

PLCG1

Phospholipase C, gamma 1, also known as PLCG1, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [cite web | title = Entrez Gene: PLCG1 phospholipase C, gamma 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5335| accessdate = ]

ee also

* Phospholipase C

References

PBB_Further_reading
citations =

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • PLCG1 — Fosfoinosítido fosfolipasa C gamma 1[1] HUGO 9065 Símbolo PLCG1 …   Wikipedia Español

  • Hepatocyte nuclear factor 4 alpha — Hepatocyte nuclear factor 4, alpha PDB rendering based on 1m7w …   Wikipedia

  • Epidermal growth factor receptor — This article is about a cell surface receptor. For estimated measure of kidney function (eGFR), see Glomerular filtration rate. Epidermal growth factor receptor …   Wikipedia

  • SH2 domain — Pfam box Symbol = SH2 Name = width = 220 caption = SH2 domain of human P56 Lck tyrosine kinase Pfam= PF00017 InterPro= IPR000980 SMART= SH2 PROSITE=PDOC50001 SCOP = 1sha TCDB = OPM family= OPM protein= 1xa6 PDB=PDB3|1k9aB:82 156 PDB3|1jwoA:122… …   Wikipedia

  • Phosphoinositide phospholipase C — Pfam box Symbol = PI PLC X Name = Phosphatidylinositol specific phospholipase C width = 220px caption =Phospholipase Cδ 1 Pfam= PF00388 InterPro= IPR000909 SMART= PLCXc PROSITE = PDOC50007 SCOP = 1gym TCDB = OPM family= 126 OPM protein= 2plc… …   Wikipedia

  • Pleckstrin homology domain — Pfam box Symbol = PH Name = width =250 caption =PH domain of tyrosine protein kinase BTK Pfam= PF00169 InterPro= IPR001849 SMART= PH PROSITE=PDOC50003 SCOP = 1dyn TCDB = OPM family= 51 OPM protein= 1pls PDB=PDB3|1dynB:520 625 PDB3|2dynA:520 625… …   Wikipedia

  • C2 domain — Pfam box Symbol = C2 Name = C2 domain width =200 caption = The C2 domain of C.absonum α toxin (PDB 1OLP). β strands are shown in yellow. Co ordinated Calcium ions are in cyan Pfam= PF00168 InterPro= IPR000008 SMART= C2 PROSITE = PDOC00380 SCOP =… …   Wikipedia

  • PLCG2 — Phospholipase C, gamma 2 (phosphatidylinositol specific), also known as PLCG2, is a human gene.cite web | title = Entrez Gene: PLCG2 phospholipase C, gamma 2 (phosphatidylinositol specific)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • PTPRJ — Protein tyrosine phosphatase, receptor type, J, also known as PTPRJ, is a human gene.cite web | title = Entrez Gene: PTPRJ protein tyrosine phosphatase, receptor type, J| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • SH2B3 — SH2B adaptor protein 3, also known as SH2B3, is a human gene.cite web | title = Entrez Gene: SH2B3 SH2B adaptor protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=10019| accessdate = ] PBB Summary… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”