Acyl-CoA dehydrogenase (NADP+)

Acyl-CoA dehydrogenase (NADP+)

In enzymology, an acyl-CoA dehydrogenase (NADP+) (EC number| is an enzyme that catalyzes the chemical reaction

:acyl-CoA + NADP+ ightleftharpoons 2,3-dehydroacyl-CoA + NADPH + H+

Thus, the two substrates of this enzyme are acyl-CoA and NADP+, whereas its 3 products are 2,3-dehydroacyl-CoA, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-CoA:NADP+ 2-oxidoreductase. Other names in common use include 2-enoyl-CoA reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide, phosphate), enoyl coenzyme A reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, and acyl-CoA dehydrogenase (NADP+).

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1YXM.



External links

::"The CAS registry number for this enzyme class is CAS registry|37251-07-3."

Gene Ontology (GO) codes

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