(-)-menthol dehydrogenase

(-)-menthol dehydrogenase
Identifiers
EC number	1.1.1.207
CAS number	81811-46-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a (-)-menthol dehydrogenase (EC 1.1.1.207) is an enzyme that catalyzes the chemical reaction

(-)-menthol + NADP⁺ $\rightleftharpoons$ (-)-menthone + NADPH + H⁺

Thus, the two substrates of this enzyme are (-)-menthol and NADP⁺, whereas its 3 products are (-)-menthone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (-)-menthol:NADP+ oxidoreductase. This enzyme is also called monoterpenoid dehydrogenase. This enzyme participates in monoterpenoid biosynthesis.

References

• Kjonaas R, Martinkus-Taylor C and Croteau R (1982). "Metabolism of monoterpenes: conversion of l-menthone to l-menthol and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves". Plant Physiol. 69 (5): 1013–1017. doi:10.1104/pp.69.5.1013. JSTOR 4267341. PMC 426349. PMID 16662335. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=426349. 

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