(+)-borneol dehydrogenase

(+)-borneol dehydrogenase
(+)-borneol dehydrogenase
Identifiers
EC number 1.1.1.198
CAS number 67185-75-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a (+)-borneol dehydrogenase (EC 1.1.1.198) is an enzyme that catalyzes the chemical reaction

(+)-borneol + NAD+ \rightleftharpoons (+)-camphor + NADH + H+

Thus, the two substrates of this enzyme are (+)-borneol and NAD+, whereas its 3 products are (+)-camphor, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-borneol:NAD+ oxidoreductase. This enzyme is also called bicyclic monoterpenol dehydrogenase.

References

  • Croteau R, Hooper CL, Felton M (1978). "Biosynthesis of monoterpenes. Partial purification and characterization of a bicyclic monoterpenol dehydrogenase from sage (Salvia officinalis)". Arch. Biochem. Biophys. 188 (1): 182–93. doi:10.1016/0003-9861(78)90371-5. PMID 677891. 
  • Dehal SS, Croteau R (1987). "Metabolism of monoterpenes: specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone". Arch. Biochem. Biophys. 258 (1): 287–91. doi:10.1016/0003-9861(87)90346-8. PMID 3310901. 

External links

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