21-hydroxysteroid dehydrogenase (NADP+)
- 21-hydroxysteroid dehydrogenase (NADP+)
In enzymology, a 21-hydroxysteroid dehydrogenase (NADP+) (EC number|1.1.1.151) is an enzyme that catalyzes the chemical reaction
:pregnan-21-ol + NADP+ pregnan-21-al + NADPH + H+
Thus, the two substrates of this enzyme are pregnan-21-ol and NADP+, whereas its 3 products are pregnan-21-al, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 21-hydroxysteroid:NADP+ 21-oxidoreductase. Other names in common use include 21-hydroxy steroid dehydrogenase, 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate), dehydrogenase, 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide, phosphate), NADP+-21-hydroxysteroid dehydrogenase, and 21-hydroxysteroid dehydrogenase (NADP+).
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|37250-76-3."
Gene Ontology (GO) codes
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