3beta(or 20alpha)-hydroxysteroid dehydrogenase

In enzymology, a 3beta(or 20alpha)-hydroxysteroid dehydrogenase (EC number|1.1.1.210) is an enzyme that catalyzes the chemical reaction

:5alpha-androstan-3beta,17beta-diol + NADP⁺ $ightleftharpoons$ 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H⁺

Thus, the two substrates of this enzyme are 5alpha-androstan-3beta,17beta-diol and NADP⁺, whereas its 3 products are 17beta-hydroxy-5alpha-androstan-3-one, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor, more specifically it is part of the group of hydroxysteroid dehydrogenases. The systematic name of this enzyme class is 3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase. Other names in common use include progesterone reductase, dehydrogenase, 3beta,20alpha-hydroxy steroid, and 3beta,20alpha-hydroxysteroid oxidoreductase.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|82869-26-9."

Gene Ontology (GO) codes