D-xylose 1-dehydrogenase

D-xylose 1-dehydrogenase
Identifiers
EC number	1.1.1.175
CAS number	62931-20-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a D-xylose 1-dehydrogenase (EC 1.1.1.175) is an enzyme that catalyzes the chemical reaction

D-xylose + NAD⁺ $\rightleftharpoons$ D-xylonolactone + NADH + H⁺

Thus, the two substrates of this enzyme are D-xylose and NAD⁺, whereas its 3 products are D-xylonolactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-xylose:NAD+ 1-oxidoreductase. Other names in common use include NAD+-D-xylose dehydrogenase, D-xylose dehydrogenase, and (NAD+)-linked D-xylose dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.

References

• Yamanaka K, Gino M and Kaneda R (1977). "A specific NAD-D-xylose dehydrogenase from Arthrobacter sp". Agric. Biol. Chem. 41: 1493–1499. 

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