Meromyosin

Meromyosin

Meromyosin (mero meaning "part of") are subunits of the actin-associated motor protein, myosin formed by trypsin digestion (proteolysis). Following digestion, two types of meromyosin are formed: heavy meromyosin (HMM) and light meromyosin (LMM).

Light meromyosin has a long, straight portion in the “tail” region. Heavy meromyosin is a protein chain terminating in a globular head portion/cross bridge. HMM consists of two subunits, Heavy Meromyosin Subunit 1 and 2 (HMMS-1 and HMMS-2). The majority of myosin activity is concentrated in HMMS-1. HMMS-1 has an Actin binding site and ATP binding site (myosin ATPase) that determines the rate of muscle contraction when muscle is stretched.



Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • meromyosin — A subunit of the tryptic digestion of myosin; two types are produced, H m. and L m.. H m., heavy m. one of the relatively heavy products (mol. wt. about 350,000) of the action of trypsin on myosin; it carries the ATPase activity of myosin …   Medical dictionary

  • meromyosin — Fragments of myosin formed by trypsin digestion. Heavy meromyosin (HMM) has the hinge region and ATPase activity, light meromyosin (LMM) is mostly a helical and is the portion normally laterally associated with other LMM to form the thick… …   Dictionary of molecular biology

  • meromyosin — noun Date: 1952 either of two structural subunits of myosin that are obtained especially by tryptic digestion …   New Collegiate Dictionary

  • meromyosin — mer·o·my·o·sin (mĕr ə mīʹə sĭn) n. Either of two protein subunits of a myosin molecule, obtained especially through the digestive action of trypsin. * * * …   Universalium

  • meromyosin — noun Either of the two subunits of myosin that are formed by the action of trypsin …   Wiktionary

  • meromyosin — mero·myosin …   English syllables

  • meromyosin — ˌmerəˌ noun Etymology: mer (III) + myosin : either of two structural subunits of myosin obtained especially by tryptic digestion …   Useful english dictionary

  • Heavy meromyosin — (HMM) is the larger of the two fragments obtained from the muscle protein myosin II following limited proteolysis by trypsin or chymotrypsin. HMM is used to determine the polarity of actin filaments by decorating them with HMM then viewing them… …   Wikipedia

  • S2 — Fibrous fragment of heavy meromyosin (HMM). Links the S1 head to the light meromyosin (LMM) region that lies in the body of the thick filament and acts as a flexible hinge …   Dictionary of molecular biology

  • HMM — may mean: * Hammerton railway station, England; National Rail station code HMM. * Hidden Markov model, a statistical model. * Heroes of Might and Magic, a series of turn based strategy games by New World Computing. * Marine Medium Helicopter… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”