- Maslinic acid
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Maslinic acid (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acidIdentifiers CAS number 4373-41-5 PubChem 73659 ChEMBL CHEMBL201515 Jmol-3D images Image 1 - CC1(C)[C@@H](O)[C@H](O)C[C@@]2(C)[C@]([H])1CC[C@]3(C)[C@@]([H])2CC=C4[C@](C)3CC[C@]5([C@](O)=O)[C@]([H])4CC(C)(C)CC5
Properties Molecular formula C30H48O4 Molar mass 472.70 g/mol acid (verify) (what is:
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Maslinic acid is a compound derived from dry olive-pomace oil (an olive skin wax) which is a byproduct of olive oil extraction. It is a member of the group of triterpenes known as oleananes.
Biological activities
Research at the University of Granada and Hospital Carlos III in Madrid indicates that maslinic acid inhibits serine proteases, key enzymes necessary for the spread of HIV within an individual's body.[1]
Also, research at the University of Barcelona suggests that maslinic acid may prevent colon cancer by acting as an antiproliferative of colon cancer cells.[2]
References
- ^ "Compound From Olive-pomace Oil Inhibits HIV Spread". sciencedaily.com. http://www.sciencedaily.com/releases/2007/07/070709111536.htm. Retrieved 2009-06-16.
- ^ Juan ME, et al. (2008). "Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells". Br J Nutr 100 (1): 36–43. doi:10.1017/S0007114508882979. PMID 18298868.
Categories:- Triterpenes
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