- Migrastatin
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Migrastatin Identifiers ChemSpider 21106454 Jmol-3D images Image 1 - C[C@@H]1/C=C(\[C@H](OC(=O)/C=C/CC/C=C/[C@@H]([C@H]1O)OC)[C@H](C)C(=O)CCCC2CC(=O)NC(=O)C2)/C
- InChI=1S/C27H39NO7/c1-17-14-18(2)27(35-25(32)13-8-6-5-7-12-22(34-4)26(17)33)19(3)21(29)11-9-10-20-15-23(30)28-24(31)16-20/h7-8,12-14,17,19-20,22,26-27,33H,5-6,9-11,15-16H2,1-4H3,(H,28,30,31)/b12-7+,13-8+,18-14-/t17-,19-,22+,26+,27+/m1/s1
Key: OGYMUMAKGYYNHV-IJMHZYIBSA-N
InChI=1/C27H39NO7/c1-17-14-18(2)27(35-25(32)13-8-6-5-7-12-22(34-4)26(17)33)19(3)21(29)11-9-10-20-15-23(30)28-24(31)16-20/h7-8,12-14,17,19-20,22,26-27,33H,5-6,9-11,15-16H2,1-4H3,(H,28,30,31)/b12-7+,13-8+,18-14-/t17-,19-,22+,26+,27+/m1/s1
Key: OGYMUMAKGYYNHV-IJMHZYIBBB
Properties Molecular formula C27H39NO7 Molar mass 489.60 g/mol (verify) (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Migrastatin is an organic compound which naturally occurs in the Streptomyces platensis bacteria. Migrastatin and several of its analogues (including Isomigrastatin) have shown to have potential in treating cancer, as it inhibits the metastasis of cancer cells.[1]
References
- ^ Shan, D et al (2005). "Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice". PNAS 102 (10): 3772–3776. doi:10.1073/pnas.0500658102. PMC 553334. PMID 15728385. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=553334.
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