RNase E 5' UTR element

RNase E 5' UTR element

RNase E 5' UTR is cis-acting element located in the 5'UTR of ribonuclease (RNase) E messenger RNA (mRNA).

RNase E is a key regulatory enzyme in the pathway of mRNA degradation in "Escherichia coli" . Its is able to auto-regulate the degradation of its own mRNA in response to changes in RNase E activity. This rne 5' UTR element acts as a sensor of cellular RNase E concentration enabling tight regulation of RNase E concentration and synthesis cite journal | author = Diwa A, Bricker AL, Jain C, Belasco JG | title = An evolutionarily conserved RNA stem-loop functions as a sensor that directs feedback regulation of RNase E gene expression | journal = Genes Dev. | volume = 14 | issue = 10 | pages = 1249–60 | year = 2000 | pmid = 10817759 | doi = | issn = ] .

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