Autophagy network

Autophagy network consists of enzymes and substrates involved in the degradation of a cell's own components.

Network members

The Autophagy network members (gene name and aliases) as published in the last 500 newest PubMed entries (see below) are depicted organically by Cytoscape in the figure on the right and are listed below as annotated by Gene Ontology.
*pdcd8 = pdcd8, aif
*egf = urg, egf
*pax2 = pax2
*gapd = gapdh, g3pd, gapd
*pik3ca = p110-alpha, pi3k, pi3-k, pik3ca
*lck = lck
*cd4 = cd4
*cxcr4 = whim, hsy3rr, lestr, npy3r, d2s201e, npyy3r, hm89, cxcr4
*eif4g1 = eif4g, p220, eif4g1
*tnfrsf5 = cdw40, cd40, p50, tnfrsf5, mgc9013
*rab7 = rab7, pro2706
*pik3c3 = pik3c3, vps34
*epha3 = tyro4, epha3, hek4, etk1, hek
*prkar1a = mgc17251, prkar1a, tse1, pkr1, cnc1, prkar1
*gclc = glclc, gclc, gcs, glcl, gd:gclc
*dnch1 = dyhc, dhc1a, dnecl, dhc1, p22, dnch1, kiaa0325, dncl, dnchc1, hl-3
*casp3 = cpp32b, sca-1, casp-3, cpp32, apopain, casp3
*cd33 = p67, cd33, siglec-3
*prkaa2 = ampk, ampk2, prkaa, prkaa2
*bcl2l11 = bcl2l11, bim, bod, biml, bimel
*pmaip1 = noxa, pmaip1
*raptor = kiaa1303, raptor
*cflar = cash, i-flice, mrit, cflar, flame, casp8ap1, flip, casper, flame-1, clarp, usurpin
*fadd = mgc8528, mort1, fadd
*tnfrsf6 = fas, tnfrsf6, apo-1, fas1, apt1, fastm, cd95, alps1a
*elf3 = ert, esx, ese-1, elf3
*ccr5 = ckr-5, cc-ckr-5, ccckr5, ccr5, ckr5, cmkbr5, cd195
*mapk8 = jnk, sapk1, jnk1, mapk8, jnk1a2, jnk21b1/2, prkm8
*ern1 = ire1p, flj30999, ire1, ern1
*rorc = rorg, rzrg, nr1f3, rorc, tor
*fpr1 = fpr1, fmlp, fpr
*lamp2 = lampb, lamp-2, lamp2
*arh = mgc34705, fhcb2, arh, dkfzp586d0624, arh2
*sac = sac, hca2
*snx13 = snx13, kiaa0713, rgs-px1
*pitx2 = ptx2, ihg2, arp1, rieg1, rgs, idg2, otlx2, rieg, pitx2, irid2, igds, mgc20144, brx1, rs, igds2
*hspca = hspc1, hsp90a, lap2, hsp90, flj31884, hsp89, hspca, hsp86, hspn
*gas2 = mgc32610, gas2
*mapk14 = rk, sapk2a, mxi2, cspb1, p38, csbp1, exip, mapk14, p38alpha, prkm14, prkm15, csbp2
*map2k1 = map2k1, mapkk1, mkk1, prkmk1, mek1
*uvrag = uvrag
*egfr = egfr, mena, erbb, erbb1
*src = src, c-src, src1, asv, p60-src
*pbx1 = pbx1
*hoxa1 = hox1, mgc45232, hox1f, hoxa1
*ifng = ifn gamma, ifngamma, ifi, ifg, ifn-gamma, ifng
*mtb = flj20311, mtb
*gabar

*cdc2 = cdc2, cdk1
*cdc25c = cdc25, cdc25c
*chek2 = rad53, pp1425, chk2, hucds1, chek2
*eif4ebp1 = eif4ebp1, phas-i, 4ebp1, 4e-bp1
*sts-1 = kiaa1959, mgc15437, sts-1, p70
*cdkn1a = cdkn1a, sdi1, mda-6, waf1, cip1, cdkn1, cap20, p21
*il2 = il2, tcgf, il-2
*pten = bzs, mgc11227, pten, mmac1, mham, pten1
*elf4 = mef, elf4, elfr
*tnfsf5 = higm1, cd40l, t-bam, igm, gp39, tnfsf5, imd3, hcd40l, cd154, cd40lg
*tnf = dif, tnf, tnfsf2
*mdcr = mds, mdcr, lis1
*syt1 = syt1, p65, svp65
*ikbkb = ikk2, ikkb, ikk-beta, nfkbikb, ikbkb
*chuk = ikbka, nfkbika, tcf16, ikk1, chuk
*cdk5r2 = nck5ai, cdk5r2, p39, p39nck5ai
*cdkn1b = cdkn1b, cdkn4, p27kip1, kip1
*atp8a2 = ib, atp8a2, atp, dkfzp434b1913, ml-1, atpib
*ifn-alpha = ifn-alpha, interferon alpha, ifna, ifn alpha, ifnalpha, interferon-alpha
*gsk3b = gsk3b, gsk3beta, gsk3-beta, gsk-3beta
*msh2 = hnpcc1, fcc1, coca1, msh2
*cldn5 = cpetrl1, bec-1, bec1, awal, cldn5, tmvcf
*ulk1 = unc51.1, ulk1, unc51, unc-51
*gng11 = g protein, gng11
*eif4g2 = dap5, eif4g2, p97
*rps6kb1 = p70-s6k, stk14a, rps6kb1, s6k1, s6k, p70-alpha, p70(s6k)-alpha, ps6k
*bcr = bcr, phl, bcr1, d22s11, cml, all, d22s662
*hdac9 = kiaa0744, hdac7b, hd7, hdac9fl, hdac9b, hdac7, hdrp, mitr, hdac9, hdac
*abl1 = p150, jtk7, c-abl, abl, abl1, v-abl
*tgm2 = tgm2, tgc, tg2, gd:tgm2
*rheb = rheb2, rheb
*tsc1 = kiaa0243, lam, hamartin, tsc1
*stk11 = lkb1, pjs, stk11

ee also

*Autophagy
*Autophagin
*Apoptosis
*Ubiquitin
*SUMO network
*Metabolic network
*Metabolic network modelling
*Protein-protein interaction

References

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