BECN1

BECN1

Beclin 1 (coiled-coil, myosin-like BCL2 interacting protein), also known as BECN1, is a human gene.cite web | title = Entrez Gene: BECN1 beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8678| accessdate = ] PBB_Summary
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Beclin-1 is also known as autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy.

References

Further reading

PBB_Further_reading
citations =
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*cite journal | author=Kruse KB, Brodsky JL, McCracken AA |title=Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. |journal=Mol. Biol. Cell |volume=17 |issue= 1 |pages= 203–12 |year= 2006 |pmid= 16267277 |doi= 10.1091/mbc.E04-09-0779
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*cite journal | author=Daniel F, Legrand A, Pessayre D, "et al." |title=Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells. |journal=World J. Gastroenterol. |volume=12 |issue= 18 |pages= 2895–900 |year= 2006 |pmid= 16718815 |doi=

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