BECN1

BECN1

Beclin 1 (coiled-coil, myosin-like BCL2 interacting protein), also known as BECN1, is a human gene.cite web | title = Entrez Gene: BECN1 beclin 1 (coiled-coil, myosin-like BCL2 interacting protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8678| accessdate = ] PBB_Summary
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Beclin-1 is also known as autophagy-related gene (Atg) 6. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagasome in autophagy.

References

Further reading

PBB_Further_reading
citations =
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*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
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*cite journal | author=Song H, Xia SL, Liao C, "et al." |title=Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma. |journal=World J. Gastroenterol. |volume=10 |issue= 4 |pages= 509–13 |year= 2004 |pmid= 14966907 |doi=
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*cite journal | author=Furuya D, Tsuji N, Yagihashi A, Watanabe N |title=Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity. |journal=Exp. Cell Res. |volume=307 |issue= 1 |pages= 26–40 |year= 2005 |pmid= 15922724 |doi= 10.1016/j.yexcr.2005.02.023
*cite journal | author=Kruse KB, Brodsky JL, McCracken AA |title=Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. |journal=Mol. Biol. Cell |volume=17 |issue= 1 |pages= 203–12 |year= 2006 |pmid= 16267277 |doi= 10.1091/mbc.E04-09-0779
*cite journal | author=Zeng X, Overmeyer JH, Maltese WA |title=Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. |journal=J. Cell. Sci. |volume=119 |issue= Pt 2 |pages= 259–70 |year= 2006 |pmid= 16390869 |doi= 10.1242/jcs.02735
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*cite journal | author=Daniel F, Legrand A, Pessayre D, "et al." |title=Partial Beclin 1 silencing aggravates doxorubicin- and Fas-induced apoptosis in HepG2 cells. |journal=World J. Gastroenterol. |volume=12 |issue= 18 |pages= 2895–900 |year= 2006 |pmid= 16718815 |doi=

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