ATG12

ATG12 autophagy related 12 homolog (S. cerevisiae), also known as ATG12, is a human gene.cite web | title = Entrez Gene: ATG12 ATG12 autophagy related 12 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9140| accessdate = ]

PBB_Summary
section_title =
summary_text = Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998). [supplied by OMIM] cite web | title = Entrez Gene: ATG12 ATG12 autophagy related 12 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9140| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Prigione A, Cortopassi G |title=Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12. |journal=Autophagy |volume=3 |issue= 4 |pages= 377–80 |year= 2007 |pmid= 17457038 |doi=
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Mizushima N, Kuma A, Kobayashi Y, "et al." |title=Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. |journal=J. Cell. Sci. |volume=116 |issue= Pt 9 |pages= 1679–88 |year= 2004 |pmid= 12665549 |doi=
*cite journal | author=Mizushima N, Yoshimori T, Ohsumi Y |title=Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. |journal=FEBS Lett. |volume=532 |issue= 3 |pages= 450–4 |year= 2003 |pmid= 12482611 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tanida I, Nishitani T, Nemoto T, "et al." |title=Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 5 |pages= 1164–70 |year= 2002 |pmid= 12207896 |doi=
*cite journal | author=Tanida I, Tanida-Miyake E, Nishitani T, "et al." |title=Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs. |journal=Biochem. Biophys. Res. Commun. |volume=292 |issue= 1 |pages= 256–62 |year= 2002 |pmid= 11890701 |doi=
*cite journal | author=Tanida I, Tanida-Miyake E, Komatsu M, "et al." |title=Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p. |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 13739–44 |year= 2002 |pmid= 11825910 |doi= 10.1074/jbc.M200385200
*cite journal | author=Mizushima N, Sugita H, Yoshimori T, Ohsumi Y |title=A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. |journal=J. Biol. Chem. |volume=273 |issue= 51 |pages= 33889–92 |year= 1999 |pmid= 9852036 |doi=
*cite journal | author=Ueno K, Kumagai T, Kijima T, "et al." |title=Cloning and tissue expression of cDNAs from chromosome 5q21-22 which is frequently deleted in advanced lung cancer. |journal=Hum. Genet. |volume=102 |issue= 1 |pages= 63–8 |year= 1998 |pmid= 9490301 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=

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