"Trans"-splicing is a special form of RNA processing in
In contrast "normal" ("cis"-)splicing processes a single molecule. That is, "trans"-splicing results in an RNA transcript that came from multiple RNA polymerases on the genome. This phenomenon can be exploited for molecular therapy to address mutated gene products.
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trans-splicing — trans splicing. См. транс сплайсинг. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
trans-splicing — (of RNA) Splicing of two different pre mRNA molecules together. Seems to rely on intron like sequences. Contrasts with the normal cis splicing of conventional RNA molecules … Dictionary of molecular biology
trans-splicing — Formation of spliced products containing portions of two different transcripts … Medical dictionary
Trans-Spliced Exon Coupled RNA End Determination (TEC-RED) — Trans Spliced Exon Coupled RNA End Determination is a technique designed by Muller et al. that, like SAGE, allows for the digital detection of messenger RNA sequences. Unlike SAGE, detection and purification of transcripts from the 5’ end of the… … Wikipedia
Splicing de ARN — El splicing de ARN o empalme de ARN(del inglés RNA splicing) es un proceso post transcripcional de corte y empalme de ARN. Este proceso es muy común en eucariotas, pudiéndose dar en cualquier tipo de ARN aunque es más común en el ARNm. También se … Wikipedia Español
RNA splicing — In molecular biology and genetics, splicing is a modification of an RNA after transcription, in which introns are removed and exons are joined. This is needed for the typical eukaryotic messenger RNA before it can be used to produce a correct… … Wikipedia
Protein splicing — is an intramolecular reaction of a particular protein in which an internal protein segment (called an intein) is removed from a precursor protein with a ligation of C terminal and N terminal external proteins (called exteins) on both sides. The… … Wikipedia
Alternative splicing — produces two protein isoforms. Alternative splicing (or differential splicing) is a process by which the exons of the RNA produced by transcription of a gene (a primary gene transcript or pre mRNA) are reconnected in multiple ways during RNA… … Wikipedia
транс-сплайсинг — trans splicing транс сплайсинг. Процесс соединения в одной молекуле мРНК последовательностей экзонов разных генов; Т. с. впервые обнаружен in vitro и заключается в соединении комплементарных участков интронных областей 2 процессируемых молекул… … Молекулярная биология и генетика. Толковый словарь.
Transspleißen — Als Transspleißen wird das Zusammenfügen von Exons verschiedener mRNAs bezeichnet. Im Gegensatz zum normalen cis Splicing werden hier also Exons unterschiedlicher RNAs, die aber vom selben Gen stammen können, miteinander verknüpft. Das… … Deutsch Wikipedia
