Enteroendocrine cells

Enteroendocrine cells are specialized endocrine cells of the gastrointestinal tract. They produce hormones such as serotonin [UIUCHistologySubject|321] , somatostatin, motilin, cholecystokinin, gastric inhibitory peptide, neurotensin, vasoactive intestinal peptide, and enteroglucagon.

Most enteroendocrine cells are found in the islets of Langerhans, but they are also found in other locations. For example, the G cells (which secrete gastrin) are located primarily in the stomach. [Medcyclopaedia|iv_1/g/G_cell] Enteroendocrine cells are also found in the duodenum. [BUHistology|11604loa - "Endocrine System: duodenum, enteroendocrine cells"]

Enterochromaffin-like cell and enterochromaffin cells are also considered enteroendocrine cells. [MeshName|Enteroendocrine+cells]

Pathology

Rare and slow growing carcinoid tumors develop from these cells. When a tumor arises it has the capacity to secrete large volumes of hormones.

ee also

* APUD cell

References