Retinopathy

Retinopathy

-ICD9|362.2

Retinopathy is a general term that refers to some form of non-inflammatory damage to the retina of the eye. Most commonly it is a problem with the blood supply that is the cause for this condition.Frequently, retinopathy is an ocular manifestation of systemic disease.

Pathophysiology

Main causes of retinopathy are : Fact|date=June 2008
* diabetes - diabetic retinopathy
* arterial hypertension - hypertensive retinopathy
* prematurity of the newborn - retinopathy of prematurity (ROP)
* sickle cell anemia
* genetic retinopathy
* direct sunlight exposure - solar retinopathy
* medicinal products - drug-related retinopathy
* retinal vein or artery occlusion

Many types of retinopathy are progressive and may result in blindness or severe vision loss or impairment, particularly if the macula becomes affected.Fact|date=June 2008

Retinopathy is diagnosed by an optometrist or an ophthalmologist during ophthalmoscopy. Treatment depends on the cause of the disease.

Relation of genetic retinopathies to other rare genetic disorders

Recent findings in genetic research have suggested that a large number of genetic disorders, both genetic syndromes and genetic diseases, that were not previously identified in the medical literature as related, may be, in fact, highly related in the genetypical root cause of the widely-varying, phenotypically-observed disorders. Thus, some genetically-caused retinopathies are the result of one or more underlying ciliopathies, an emerging new class of human genetic disorders. Other known ciliopathies include primary ciliary dyskinesia, Bardet-Biedl syndrome, polycystic kidney and liver disease, nephronophthisis, Alstrom syndrome, and Meckel-Gruber syndrome. [cite journal
last = Badano
first = Jose L.
authorlink =
coauthors = Norimasa Mitsuma, Phil L. Beales, Nicholas Katsanis
title = The Ciliopathies : An Emerging Class of Human Genetic Disorders
journal = Annual Review of Genomics and Human Genetics
volume = 7
issue =
pages = 125-148
publisher =
location =
date = September 2006
url = http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.genom.7.080505.115610
doi = 10.1146/annurev.genom.7.080505.115610
id =
accessdate = 2008-06-15] .

References

ee also

*List of eye diseases and disorders
*List of systemic diseases with ocular manifestations

External links

* [http://www.eyetalk.co.uk Eyetalk - Forum for Retinal Screeners]
* [http://www.hhmi.org/bulletin/sept2005/features/cilia.html The Importance of Being Cilia] Accessible article at Howard Hughes Medical Institute on the importance and extensive use of cilia and basal bodies in many organ systems of human physiology, including for transfer of retinal nutrients.


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Look at other dictionaries:

  • retinopathy — [ret΄ n äp′ə thē] n. pl. retinopathies any disease, inflammation, etc. of the retina …   English World dictionary

  • retinopathy — Noninflammatory degenerative disease of the retina. [retino + G. pathos, suffering] arteriosclerotic r. r. distinguished by attenuated retinal arterioles with increased tortuosity, copper or silver wire appearance, perivascular sheathing,… …   Medical dictionary

  • retinopathy — n. any of various disorders of the retina resulting in impairment or loss of vision. It is usually due to damage to the blood vessels of the retina, occurring (for example) as a complication of longstanding diabetes (diabetic retinopathy), high… …   The new mediacal dictionary

  • retinopathy — noun a disease of the retina that can result in loss of vision • Hypernyms: ↑eye disease • Hyponyms: ↑diabetic retinopathy …   Useful english dictionary

  • retinopathy of prematurity — n an ocular disorder of premature infants that occurs when the incompletely vascularized retina of such an infant completes an abnormal pattern of vascularization and that is characterized by the presence of an opaque fibrous membrane behind the… …   Medical dictionary

  • Retinopathy of prematurity — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 11442 ICD10 = ICD10|H|35|1|h|30 ICD9 = ICD9|362.21 ICDO = OMIM = MedlinePlus = eMedicineSubj = oph eMedicineTopic = 413 eMedicine mult = eMedicine2|ped|1998 | MeshID = D012178 Retinopathy of… …   Wikipedia

  • retinopathy of prematurity — ▪ pathology also called  ROP        disease in which retinal blood vessels (blood vessel) develop abnormally in the eyes of premature infants (premature birth and postmature birth). In mild forms of retinopathy of prematurity, developing blood… …   Universalium

  • retinopathy — noun (plural thies) Date: 1932 any of various noninflammatory disorders of the retina including some that cause blindness …   New Collegiate Dictionary

  • retinopathy — /ret n op euh thee/, n. Ophthalm. any diseased condition of the retina, esp. one that is noninflammatory. [1930 35; RETIN(A) + O + PATHY] * * * …   Universalium

  • retinopathy — noun /ˌɹɛtɨnˈɑːpəθi/ Non inflammatory disease of the retina …   Wiktionary

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