Traumatic acid

Traumatic acid

Chembox new
Reference = ["Merck Index", 11th Edition, 9493]
ImageFile = Traumatic acid structure.png ImageSize = 250px
IUPACName = Dodec-2-enedioic acid
OtherNames = "trans"-Traumatic acid
Section1 = Chembox Identifiers
CASNo = 6402-36-4
PubChem = 5283028
SMILES = O=C(O)/C=C/CCCCCCCCC(O)=O
Section2 = Chembox Properties
Formula = C12H20O4
MolarMass = 228.28
Appearance =
Density =
MeltingPt = 166-167 °C
BoilingPt = 150-160 °C at 0.001 mmHg
Solubility = Sparingly soluble
Section3 = Chembox Hazards
MainHazards =
FlashPt =
Autoignition =

Traumatic acid is a monounsaturated dicarboxylic acid naturally occurring in plants. The compound was first isolated from wounded bean plants by American chemists James English Jr. and James Frederick Bonner and Dutch scientist Arie Jan Haagen-Smit in 1939. [English J Jr., Bonner J, Haagen-Smit AJ: Structure and synthesis of a plant wound hormone. "Science" 90:329. (1939)] Traumatic acid is a potent wound healing agent in plants ("wound hormone") that stimulates cell division near a trauma site to form a protective callus and to heal the damaged tissue. It may also act as a growth hormone, especially in inferior plants (e.g. algae). Traumatic acid is biosynthesized in plants by non-enzymatic oxidation of traumatin (12-oxo-"trans"-10-dodecanoic acid), another wound hormone.

At normal conditions, traumatic acid is a solid, crystalline, water insoluble substance.

Traumatic acid is used as an intermediate in prostaglandin synthesis. It is also a constituent of some pharmaceutical products, such as the odontostomatologic gel Restomyl, due to its mucosal re-epithelialization activity.

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • traumatic acid — noun : a crystalline unsaturated dicarboxylic acid HOOC(CH2)8CH . CHCOOH that is obtained especially from the pods of green beans or by synthesis and that promotes healing of plant wounds; 2 dodec ene dioic acid see wound hormone …   Useful english dictionary

  • Traumatic brain injury — See also: Brain injury (disambiguation) Traumatic brain injury Classification and external resources …   Wikipedia

  • Dicarboxylic acid — Dicarboxylic acids are organic compounds that contain two carboxylic acid functional groups. In molecular formulae for dicarboxylic acids, these groups are often written as HOOC R COOH, where R may be an alkyl, alkenyl, alkynyl, or aryl group.… …   Wikipedia

  • Chronic traumatic encephalopathy — (CTE) is a progressive degenerative disease found in individuals who have been subjected to multiple concussions and other forms of head injury. A variant of the condition, dementia pugilistica, is primarily associated with boxing. CTE has been… …   Wikipedia

  • Lysergic acid diethylamide — LSD redirects here. For other uses, see LSD (disambiguation). LSD 25 redirects here. For the dock landing ship, see USS San Marcos (LSD 25). For the Fringe episode, see Lysergic Acid Diethylamide (Fringe). Lysergic acid diethylamide …   Wikipedia

  • Tranexamic acid — Systematic (IUPAC) name trans 4 (aminomethyl)cyclohexanecarboxylic acid Clinical data AHFS/ …   Wikipedia

  • Alendronic acid — Systematic (IUPAC) name sodium [4 amino 1 hydroxy 1 (hydr …   Wikipedia

  • N-Acetylaspartylglutamic acid — IUPAC name (2S) 2 [[(2S) 2 Acetamido 4 hydroxy 4 oxobutanoyl]amino]p …   Wikipedia

  • lysergic acid diethylamide (lsd) and hallucinations —    Lysergic acid diethylamide is known under many names, including LSD, LSD 25, and acid. It is usually classified as a semi synthetic psychedelic substance of the family of ergot alkaloids, as a hallucinogen or an entheogen. The ergo tamine… …   Dictionary of Hallucinations

  • List of chemical compounds with unusual names — Chemical nomenclature, replete as it is with compounds with complex names, is a repository for some very peculiar and sometimes startling names. A browse through the Physical Constants of Organic Compounds in the CRC Handbook of Chemistry and… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”