Calgranulin

Calgranulin

Calgranulin is an S-100 calcium-binding protein that is expressed in multiple cell types, including renal epithelial cells and neutrophils. Some "in vitro" evidence suggests that calgranulin can inhibit the precipitation of calcium oxalate in a urine-like environment at calgranulin concentrations below physiological concentrations. [cite journal |author=Pillay S, Asplin J, Coe F |title=Evidence that calgranulin is produced by kidney cells and is an inhibitor of calcium oxalate crystallization |journal=Am J Physiol |volume=275 |issue=2 Pt 2 |pages=F255–61 |year=1998 |pmid=9691016 |url=http://ajprenal.physiology.org/cgi/content/abstract/275/2/F255] Thus, it may also function "in vivo" as an inhibitor of calcium oxalate kidney stone formation. However, the role of calgranulin in the stone formation process has not been evaluated.

Genes

* S100A8, S100A9, S100A12

References

External links

*
*


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • calgranulin A — A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of… …   English dictionary of cancer terms

  • calgranulin B — A protein that is made by many different types of cells and is involved in processes that take place both inside and outside of the cell. It is made in larger amounts in inflammatory diseases such as rheumatoid arthritis, and in some types of… …   English dictionary of cancer terms

  • CAGA — calgranulin A …   Medical dictionary

  • CAGB — calgranulin B …   Medical dictionary

  • CAGA — • calgranulin A …   Dictionary of medical acronyms & abbreviations

  • CAGB — • calgranulin B …   Dictionary of medical acronyms & abbreviations

  • S100A12 — S100 calcium binding protein A12, also known as S100A12, is a human gene.cite web | title = Entrez Gene: S100A12 S100 calcium binding protein A12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6283|… …   Wikipedia

  • Kidney stone — Classification and external resources …   Wikipedia

  • Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia

  • Cluster of differentiation — The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells, providing targets for immunophenotyping of cells …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”