CAS number 541-91-3
Jmol-3D images Image 1
Molecular formula C16H30O
Molar mass 238.40 g/mol
Density 0.9221 g/cm3
Melting point

-15 °C, 258 K, 5 °F

Boiling point

328 °C, 601 K, 622 °F

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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Muscone is an organic compound that is the primary contributor to the odor of musk.

The chemical structure of muscone was first elucidated by Lavoslav Ružička. It consists of a 15-membered ring ketone with one methyl substituent in the 3-position. It is an oily liquid that is found naturally as the (−)-enantiomer, but synthetic material is typically a racemate. It is very slightly soluble in water and miscible with alcohol.

Natural muscone is obtained from musk, a glandular secretion of the musk deer, which has been used in perfumery and medicine for thousands of years. Since obtaining natural musk requires killing the endangered animal, nearly all muscone used in perfumery today is synthetic. It has the characteristic smell of being "Musky". One asymmetric synthesis of (−)-muscone begins with commercially available (+)-citronellal, and forms the 15-membered ring via ring-closing metathesis:[1]

Synthesis of muscone via RCM

Muscone is now produced synthetically for use in perfumes and for scenting consumer products.

See also


  1. ^ Kamat, V.P.; Hagiwara, H.; Katsumi, T.; Hoshi, T.; Suzuki, T.; Ando, M. (2000). "Ring Closing Metathesis Directed Synthesis of (R)-(−)-Muscone from (+)-Citronellal". Tetrahedron 56 (26): 4397–4403. doi:10.1016/S0040-4020(00)00333-1. 

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Look at other dictionaries:

  • Muscone — Général Nom IUPAC (R) 3 méthylcyclopentadecanone Synonymes 3 méthyl 1 cyclopen …   Wikipédia en Français

  • muscone — [myskɔn] n. f. ÉTYM. 1933, Larousse; de musc, et (cét)one. ❖ ♦ Techn. Didact. (chim.). Principe odorant du musc, cétone cyclique …   Encyclopédie Universelle

  • muscone — /mus kohn/, n. Chem. an oily, very slightly water soluble, large cyclic ketone containing a 15 membered ring, C16H30O, obtained from musk: used in the perfume industry. Also, muskone. [ < LL musc(us) MUSK + ONE] * * * …   Universalium

  • muscone — Muskone …   Medical dictionary

  • muscone — mu·scó·ne s.m. TS biochim. sostanza odorosa di natura chetonica che costituisce il principio attivo del muschio, usata in profumeria come distillato {{line}} {{/line}} DATA: 1954. ETIMO: der. di 2musco con 2 one …   Dizionario italiano

  • muscone — pl.m. musconi …   Dizionario dei sinonimi e contrari

  • muscone — mus·cone …   English syllables

  • muscone — /ˈmʌskoʊn/ (say muskohn) noun a large cyclic ketone, C16H30O, originally obtained from musk and used in the perfume industry. {Latin muscus + one} …  

  • muscone — …   Useful english dictionary

  • 541-91-3 — Muscone Muscone Général Nom IUPAC (R) 3 méthylcyclopentadecanone Synonymes 3 mét …   Wikipédia en Français

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