DNA polymerase II

This article is about the DNA Polymerase. For the RNA Polymerase, see RNA polymerase II

DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA polymerase most likely involved in DNA repair.

The enzyme is 90 kDa in size and is coded by the polB gene. DNA Pol II can synthesize DNA new base pairs at an average rate of between 40 and 50 nucleotides/second. Strains lacking the gene show no defect in growth or replication. Synthesis of Pol II is induced during the stationary phase of cell growth. This is a phase in which little growth and DNA synthesis occurs. It is also a phase in which the DNA can accumulate damage such as short gaps, which act as a block to DNA Pol III. Under these circumstances, Pol II helps to overcome the problem because it can reinitiate DNA synthesis downstream of gaps. Pol II has a low error rate but it is much too slow to be of any use in normal DNA synthesis. Pol II differs from Pol I in that it lacks a 5'->3' exonuclease activity, and cannot use a nicked duplex template.

See also

• DNA replication.

This transferase article is a stub. You can help Wikipedia by expanding it.v · Categories: DNA replication EC 2.7.7 Enzymes Transferase stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Marguerite de Navarre William M. Butler Look at other dictionaries: DNA-Polymerase — Bänderdarstellung der DNA bindenden Domäne der humanen DNA Polymerase β …   Deutsch Wikipedia DNA polymerase mu — Polymerase (DNA directed), mu PDB rendering based on 2dun …   Wikipedia DNA polymerase — (d[=e] [e^]n*[=a] p[o^]*l[i^]m [ e]r*[=a]s) n. (Biochemistry, Genetics) an enzyme that catalyzes the formation of DNA from deoxyribonucleoside triphosphates. Cells contain several types of DNA polymerase, some of which are required for… …   The Collaborative International Dictionary of English DNA polymerase — DNA polymerase. См. ДHK полимераза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь. DNA polymerase ### — DNA polymerase ###. См. ДНК полимераза ###. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь. DNA-Polymerase —  DNA Polymerase  ДНК полимераза   Фермент, катализирующий синтез полинуклеотидной цепи из отдельных нуклеотидов с использованием другой цепи в качестве матрицы и ДНК затравки со свободной 3’–ОН группой …   Толковый англо-русский словарь по нанотехнологии. - М. DNA polymerase — 3D structure of the DNA binding helix turn helix motifs in human DNA polymerase beta A DNA polymerase is an enzyme that helps catalyze in the polymerization of deoxyribonucleotides into a DNA strand. DNA polymerases are best known for their… …   Wikipedia DNA polymerase I — Functional domains in the Klenow Fragment (left) and DNA Polymerase I (right). DNA Polymerase I (or Pol I) is an enzyme that participates in the process of DNA replication in prokaryotes. It is composed of 928 amino acids, and is an example of a… …   Wikipedia DNA polymerase — Enzyme that catalyzes (speeds) the polymerization of DNA. DNA polymerase uses preexisting nucleic acid templates and assembles the DNA from deoxyribonucleotides. * * * DNA polymerase n any of several polymerases that promote replication or repair …   Medical dictionary DNA polymerase — noun the enzyme responsible for DNA replication • Hypernyms: ↑polymerase * * * noun : any of several polymerases that promote replication or repair of DNA usually using single stranded DNA as a template * * * any of a class of enzymes involved in …   Useful english dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”