PC12 cell

PC12 cell

PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla.[1][2] PC12 cells stop dividing and terminally differentiate when treated with nerve growth factor.[3] This makes PC12 cells useful as a model system for neuronal differentiation.

See also

References

  1. ^ Greene LA, Tischler AS (July 1976). "Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor". Proc. Natl. Acad. Sci. U.S.A. 73 (7): 2424–8. doi:10.1073/pnas.73.7.2424. PMC 430592. PMID 1065897. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=430592. 
  2. ^ "PC-12/CRL-1721 cell line". LGC Promochem: Cell Biology Collection. American Type Culture Collection. http://www.lgcpromochem-atcc.com/common/catalog/numSearch/numResults.cfm?atccNum=CRL-1721. Retrieved 2008-08-15. [dead link]
  3. ^ Center for Cancer Education

External links

  • Wikipedia articles containing the term "PC12 cells" [1]
  • table of common cell lines including PC12 [2], from Alberts 4th edition at NCBI bookshelf
  • Ras function was partially elucidated using PC12 cell line [3], from section in Cancer Medicine textbook
  • Section on neural transmission [4] has several references to PC12 cell line

Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • PC12 cells — PC12 is a cancer cell line derived from a pheochromocytoma of the rat adrenal medulla.cite journal | author = Greene LA, Tischler AS | title = Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to… …   Wikipedia

  • Cell culture — in a Petri dish Epithelial cells in culture, stained for keratin (red) an …   Wikipedia

  • PC12 — A rat phaeochromocytoma cell line from adrenal medulla. Widely used in the study of stimulus secretion coupling, and because it differentiates to resemble sympathetic neurons on application of nerve growth factor …   Dictionary of molecular biology

  • CRK (gene) — CRK is a gene which codes a protein exhibiting the SH2 domain. PBB Summary section title = summary text = This gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has …   Wikipedia

  • FRS2 — Fibroblast growth factor receptor substrate 2, also known as FRS2, is a human gene. [cite web | title = Entrez Gene: FRS2 Fibroblast growth factor receptor substrate 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • L-DOPA — Systematic (IUPAC) name …   Wikipedia

  • P110δ — Phosphoinositide 3 kinase, catalytic, delta polypeptide Identifiers Symbols PIK3CD; P110DELTA; PI3K; p110D External IDs …   Wikipedia

  • PIK3CB — Phosphoinositide 3 kinase, catalytic, beta polypeptide Identifiers Symbols PIK3CB; DKFZp779K1237; MGC133043; P110BETA; PI3K; PI3KBETA; PIK3C1 External IDs …   Wikipedia

  • PIK3C2A — Phosphoinositide 3 kinase, class 2, alpha polypeptide, also known as PIK3C2A, is a human gene.cite web | title = Entrez Gene: PIK3C2A phosphoinositide 3 kinase, class 2, alpha polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • PIK3C2B — Phosphoinositide 3 kinase, class 2, beta polypeptide, also known as PIK3C2B, is a human gene.cite web | title = Entrez Gene: PIK3C2B phosphoinositide 3 kinase, class 2, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”