PC12 cell

PC12 cell

PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla.[1][2] PC12 cells stop dividing and terminally differentiate when treated with nerve growth factor.[3] This makes PC12 cells useful as a model system for neuronal differentiation.

See also

References

  1. ^ Greene LA, Tischler AS (July 1976). "Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor". Proc. Natl. Acad. Sci. U.S.A. 73 (7): 2424–8. doi:10.1073/pnas.73.7.2424. PMC 430592. PMID 1065897. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=430592. 
  2. ^ "PC-12/CRL-1721 cell line". LGC Promochem: Cell Biology Collection. American Type Culture Collection. http://www.lgcpromochem-atcc.com/common/catalog/numSearch/numResults.cfm?atccNum=CRL-1721. Retrieved 2008-08-15. [dead link]
  3. ^ Center for Cancer Education

External links

  • Wikipedia articles containing the term "PC12 cells" [1]
  • table of common cell lines including PC12 [2], from Alberts 4th edition at NCBI bookshelf
  • Ras function was partially elucidated using PC12 cell line [3], from section in Cancer Medicine textbook
  • Section on neural transmission [4] has several references to PC12 cell line

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