Norleucine

Norleucine
IUPAC name 2-aminohexanoic acid
Other names Caprine Glycoleucine
Identifiers
CAS number	327-57-1 (2S)
PubChem	9475
ChemSpider	401917
UNII	832C8OV84S
EC number	210-462-7
DrugBank	DB04419
KEGG	C01933
MeSH	Norleucine
ChEBI	CHEBI:36405
RTECS number	RC6308000
Beilstein Reference	1721748
Gmelin Reference	464584
3DMet	B00369
Jmol-3D images	Image 1
SMILES CCCCC(N)C(O)=O
InChI InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9) Key: LRQKBLKVPFOOQJ-UHFFFAOYSA-N
Properties
Molecular formula	C6H13NO2
Molar mass	131.17 g mol−1
Melting point	301 °C (decomposes) [1]
Solubility in water	16 g/l at 23 °C [2]
Acidity (pKa)	2.39 (carboxyl), 9.76 (amino)[3]
Hazards
S-phrases	36/37
Related compounds
Related Aminoacids	Norvaline (2-amino-pentanoic) Aminocaproic acid (6-amino-hexanoic) Leucine (2-amino-4-methyl-pentanoic) Isoleucine (2-amino-3-methyl-pentanoic) Lysine (2,6-diamino-hexanoic)
Related compounds	Caproic acid (hexanoic)
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Norleucine (abbreviated as Nle) is an isomer of leucine, the α-amino acid 2-amino-hexanoic acid. It is not found in natural proteins. Norleucine is used in experimental studies of protein structure and function.

See also

• Leucines, description of the isomers of leucine

References

1. ^ Hermann Römpp, Jürgen Falbe und Manfred Regitz: Römpp Lexikon Chemie, 9. Auflage, Georg Thieme Verlag, Stuttgart 1992.
2. ^ Sicherheitsdatenblatt Acros.
3. ^ Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959.

This article about an organic compound is a stub. You can help Wikipedia by expanding it.v · Categories: Organic compound stubs Amino acids Wikimedia Foundation. 2010. Игры ⚽ Нужно сделать НИР? Norlander Norlevorphanol Look at other dictionaries: norleucine — norleucinas statusas T sritis chemija formulė H(CH₂)₄CH(NH₂)COOH atitikmenys: angl. norleucine rus. норлейцин ryšiai: sinonimas – 2 aminoheksano rūgštis …   Chemijos terminų aiškinamasis žodynas norleucine — (= Ahx; Nle; 2 aminohexanoic acid) Non protein amino acid. Formyl Norleucyl Leucyl Phenylalanine has been used as a substitute for fMLP in studies on neutrophil chemotaxis since it is not so susceptible to oxidation …   Dictionary of molecular biology norleucine — α Amino n caproic acid; 2 aminohexanoic acid; an α amino acid, isomer of leucine and isoleucine, but not found in proteins; a deamination product of l lysine, to which it is linked in collagens. SYN: glycoleucine. * * * nor·leu·cine ( )nȯr lü… …   Medical dictionary norleucine — nor·leucine …   English syllables norleucine — (ˈ)nȯ(r)+ noun Etymology: International Scientific Vocabulary nor + leucine : a crystalline amino acid CH3(CH2)3CH(NH2)COOH isomeric with leucine and usually made synthetically; alpha amino caproic acid …   Useful english dictionary norleu — norleucine …   Medical dictionary Nle — • norleucine …   Dictionary of medical acronyms & abbreviations norleu — • norleucine …   Dictionary of medical acronyms & abbreviations 6-Diazo-5-oxo-L-norleucin — Strukturformel Allgemeines Name 6 Diazo 5 oxo L norleucin …   Deutsch Wikipedia 2-aminohexanoate transaminase — In enzymology, a 2 aminohexanoate transaminase (EC number|2.6.1.67) is an enzyme that catalyzes the chemical reaction:L 2 aminohexanoate + 2 oxoglutarate ightleftharpoons 2 oxohexanoate + L glutamateThus, the two substrates of this enzyme are L 2 …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”