Mitotic catastrophe

Mitotic catastrophe

Mitotic catastrophe is an event in which a cell is destroyed during mitosis. This is believed by some to occur as a result of an attempt at aberrant chromosome segregation early in mitosis, or as a result of DNA damage later. Cells which fail to go through a mitotic catastrophe after a mitotic failure are likely to create aneuploid cells when they later reproduce, posing a risk of oncogenesis, potentially leading to cancer.

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