PLK2

Polo-like kinase 2 (Drosophila), also known as PLK2, is a human gene.cite web | title = Entrez Gene: PLK2 polo-like kinase 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10769| accessdate = ]

PBB_Summary
section_title =
summary_text = Serum-inducible kinase is a member of the 'polo' family of serine/threonine protein kinases that have a role in normal cell division. [supplied by OMIM] cite web | title = Entrez Gene: PLK2 polo-like kinase 2 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10769| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kauselmann G, Weiler M, Wulff P, "et al." |title=The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity. |journal=EMBO J. |volume=18 |issue= 20 |pages= 5528–39 |year= 1999 |pmid= 10523297 |doi= 10.1093/emboj/18.20.5528
*cite journal | author=Ouyang B, Li W, Pan H, "et al." |title=The physical association and phosphorylation of Cdc25C protein phosphatase by Prk. |journal=Oncogene |volume=18 |issue= 44 |pages= 6029–36 |year= 1999 |pmid= 10557092 |doi= 10.1038/sj.onc.1202983
*cite journal | author=Holtrich U, Wolf G, Yuan J, "et al." |title=Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages. |journal=Oncogene |volume=19 |issue= 42 |pages= 4832–9 |year= 2000 |pmid= 11039900 |doi= 10.1038/sj.onc.1203845
*cite journal | author=Liby K, Wu H, Ouyang B, "et al." |title=Identification of the human homologue of the early-growth response gene Snk, encoding a serum-inducible kinase. |journal=DNA Seq. |volume=11 |issue= 6 |pages= 527–33 |year= 2002 |pmid= 11696980 |doi=
*cite journal | author=Shimizu-Yoshida Y, Sugiyama K, Rogounovitch T, "et al." |title=Radiation-inducible hSNK gene is transcriptionally regulated by p53 binding homology element in human thyroid cells. |journal=Biochem. Biophys. Res. Commun. |volume=289 |issue= 2 |pages= 491–8 |year= 2002 |pmid= 11716500 |doi= 10.1006/bbrc.2001.5993
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ma S, Liu MA, Yuan YL, Erikson RL |title=The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. |journal=Mol. Cancer Res. |volume=1 |issue= 5 |pages= 376–84 |year= 2003 |pmid= 12651910 |doi=
*cite journal | author=Matsuda A, Suzuki Y, Honda G, "et al." |title=Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. |journal=Oncogene |volume=22 |issue= 21 |pages= 3307–18 |year= 2003 |pmid= 12761501 |doi= 10.1038/sj.onc.1206406
*cite journal | author=Burns TF, Fei P, Scata KA, "et al." |title=Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells. |journal=Mol. Cell. Biol. |volume=23 |issue= 16 |pages= 5556–71 |year= 2003 |pmid= 12897130 |doi=
*cite journal | author=Ma S, Charron J, Erikson RL |title=Role of Plk2 (Snk) in mouse development and cell proliferation. |journal=Mol. Cell. Biol. |volume=23 |issue= 19 |pages= 6936–43 |year= 2003 |pmid= 12972611 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Yogosawa S, Hatakeyama S, Nakayama KI, "et al." |title=Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase. |journal=J. Biol. Chem. |volume=280 |issue= 50 |pages= 41619–27 |year= 2006 |pmid= 16203730 |doi= 10.1074/jbc.M508397200
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Park YY, Kim SH, Kim YJ, "et al." |title=Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRgamma). |journal=Biochem. Biophys. Res. Commun. |volume=362 |issue= 1 |pages= 107–13 |year= 2007 |pmid= 17706602 |doi= 10.1016/j.bbrc.2007.07.170
*cite journal | author=Matthew EM, Yen TJ, Dicker DT, "et al." |title=Replication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cells. |journal=Cell Cycle |volume=6 |issue= 20 |pages= 2571–8 |year= 2007 |pmid= 17912033 |doi=

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