KIF2C

KIF2C

Kinesin family member 2C, also known as KIF2C, is a human gene.cite web | title = Entrez Gene: KIF2C kinesin family member 2C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11004| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of kinesin-like protein family. Most proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein acts to regulate microtubule dynamics in cells and is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.cite web | title = Entrez Gene: KIF2C kinesin family member 2C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11004| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Miki H, Setou M, Kaneshiro K, Hirokawa N |title=All kinesin superfamily protein, KIF, genes in mouse and human. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7004–11 |year= 2001 |pmid= 11416179 |doi= 10.1073/pnas.111145398
*cite journal | author=Kim IG, Jun DY, Sohn U, Kim YH |title=Cloning and expression of human mitotic centromere-associated kinesin gene. |journal=Biochim. Biophys. Acta |volume=1359 |issue= 3 |pages= 181–6 |year= 1998 |pmid= 9434124 |doi=
*cite journal | author=Maney T, Hunter AW, Wagenbach M, Wordeman L |title=Mitotic centromere-associated kinesin is important for anaphase chromosome segregation. |journal=J. Cell Biol. |volume=142 |issue= 3 |pages= 787–801 |year= 1998 |pmid= 9700166 |doi=
*cite journal | author=Wordeman L, Wagenbach M, Maney T |title=Mutations in the ATP-binding domain affect the subcellular distribution of mitotic centromere-associated kinesin (MCAK). |journal=Cell Biol. Int. |volume=23 |issue= 4 |pages= 275–86 |year= 2000 |pmid= 10600236 |doi= 10.1006/cbir.1999.0359
*cite journal | author=Sugata N, Li S, Earnshaw WC, "et al." |title=Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes. |journal=Hum. Mol. Genet. |volume=9 |issue= 19 |pages= 2919–26 |year= 2001 |pmid= 11092768 |doi=
*cite journal | author=Maney T, Wagenbach M, Wordeman L |title=Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin. |journal=J. Biol. Chem. |volume=276 |issue= 37 |pages= 34753–8 |year= 2001 |pmid= 11466324 |doi= 10.1074/jbc.M106626200
*cite journal | author=Cheng LJ, Zhou ZM, Li JM, "et al." |title=Expression of a novel HsMCAK mRNA splice variant, tsMCAK gene, in human testis. |journal=Life Sci. |volume=71 |issue= 23 |pages= 2741–57 |year= 2002 |pmid= 12383881 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cassimeris L, Morabito J |title=TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly. |journal=Mol. Biol. Cell |volume=15 |issue= 4 |pages= 1580–90 |year= 2004 |pmid= 14718566 |doi= 10.1091/mbc.E03-07-0544
*cite journal | author=Ganem NJ, Compton DA |title=The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. |journal=J. Cell Biol. |volume=166 |issue= 4 |pages= 473–8 |year= 2004 |pmid= 15302853 |doi= 10.1083/jcb.200404012
*cite journal | author=Newton CN, Wagenbach M, Ovechkina Y, "et al." |title=MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitro. |journal=FEBS Lett. |volume=572 |issue= 1-3 |pages= 80–4 |year= 2004 |pmid= 15304328 |doi= 10.1016/j.febslet.2004.06.093
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Moore AT, Rankin KE, von Dassow G, "et al." |title=MCAK associates with the tips of polymerizing microtubules. |journal=J. Cell Biol. |volume=169 |issue= 3 |pages= 391–7 |year= 2005 |pmid= 15883193 |doi= 10.1083/jcb.200411089
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ganem NJ, Upton K, Compton DA |title=Efficient mitosis in human cells lacking poleward microtubule flux. |journal=Curr. Biol. |volume=15 |issue= 20 |pages= 1827–32 |year= 2006 |pmid= 16243029 |doi= 10.1016/j.cub.2005.08.065
*cite journal | author=Helenius J, Brouhard G, Kalaidzidis Y, "et al." |title=The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends. |journal=Nature |volume=441 |issue= 7089 |pages= 115–9 |year= 2006 |pmid= 16672973 |doi= 10.1038/nature04736
*cite journal | author=Sun Y, Huang YC, Xu QZ, "et al." |title=HIV-1 Tat depresses DNA-PK(CS) expression and DNA repair, and sensitizes cells to ionizing radiation. |journal=Int. J. Radiat. Oncol. Biol. Phys. |volume=65 |issue= 3 |pages= 842–50 |year= 2006 |pmid= 16751065 |doi= 10.1016/j.ijrobp.2006.02.040
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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