Oncogenesis

Oncogenesis

Oncogenesis is the process of malignant transformation leading to the formation of a tumor (tumorigenesis). It is characterized by a progression of changes on cellular and genetic level that ultimately reprogram a cell to undergo uncontrolled cell division, thus forming a malignant mass.

Oncovirinae, retroviruses which contain an onc gene, are categorized as oncogenic because they trigger the growth of tumorous tissues in the host. This process is also referred to as viral transformation.

ee also

* carcinogen a substance, radionuclide or radiation directly involved in the promotion of cancer.
* mutagen a physical or chemical agent that changes the genetic information of an organism.
* teratogen
* oncogene a modified gene believed to cause cancer.

References

Hornberg, J., Binder, B., Bruggeman, F., Schoeber, B., Heinrich, R., Westerhoff, H., "Control of MAPK signalling: from complexity to what really matters", Oncogene, Vol. 24, pp 5533-5542, (published online 20June2005).


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Look at other dictionaries:

  • oncogénesis — f. oncol. Proceso de formación y desarrollo de un tumor. (Ver cáncer.) Medical Dictionary. 2011. oncogénesis …   Diccionario médico

  • oncogénesis — f. Med. Origen y producción de los tumores malignos …   Diccionario de la lengua española

  • oncogénesis — ► sustantivo femenino MEDICINA Estudio del nacimiento y origen de los tumores y de las enfermedades cancerígenas. IRREG. plural oncogénesis * * * oncogénesis. f. Med. Origen y producción de los tumores malignos. * * * ► …   Enciclopedia Universal

  • oncogenesis — noun Etymology: New Latin Date: circa 1932 the induction or formation of tumors …   New Collegiate Dictionary

  • oncogenesis — oncogenic, oncogenetic /ong keuh jeuh net ik/, adj. /ong keuh jen euh sis/, n. the generation of tumors. [1930 35; ONCO + GENESIS] * * * …   Universalium

  • oncogenesis — noun The formation and development of tumors See Also: oncogenic …   Wiktionary

  • oncogenesis — Origin and growth of a neoplasm. [onco + G. genesis, production] * * * on·co·gen·e·sis .äŋ kō jen ə səs n, pl e·ses .sēz the induction or formation of tumors * * * n. the development of a new abnormal growth (a benign or malignant tumour). * * *… …   Medical dictionary

  • oncogenesis — producing cancerous tumours Causation and Formation …   Phrontistery dictionary

  • oncogenesis — on·co·genesis …   English syllables

  • oncogenesis — n. the development of a new abnormal growth (a benign or malignant tumour) …   The new mediacal dictionary

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