1-Methyltryptophan

1-Methyltryptophan
IUPAC name 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Other names 1-Methyl-DL-tryptophan; DL-1-Methyltryptophan; ARBRIN
Identifiers
CAS number	26988-72-7 (D/L) N, 21339-55-9 (L) Y
PubChem	98112
ChemSpider	88584 Y
ChEMBL	CHEMBL504816 N, CHEMBL514172
Jmol-3D images	Image 1
SMILES O=C(O)C(N)Cc2c1ccccc1n(c2)C
InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16) Y Key: ZADWXFSZEAPBJS-UHFFFAOYSA-N Y InChI=InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16) Key: ZADWXFSZEAPBJS-UHFFFAOYSA-N
Properties
Molecular formula	C12H14N2O2
Molar mass	218.25 g mol−1
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

1-Methyltryptophan is a competitive inhibitor of indoleamine 2,3-dioxygenase (IDO or INDO EC 1.13.11.52).^[1]

References

1. ^ Cady, SG; Sono, M (1991). "1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-3-benzo(b)thienyl-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase". Archives of biochemistry and biophysics 291 (2): 326–33. doi:10.1016/0003-9861(91)90142-6. PMID 1952947. 

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This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.v · Categories: Oxidoreductase inhibitors Indoles Amino acids Antineoplastic and immunomodulating drug stubs Heterocyclic compound stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат alpha-Methylstyrene Methyltyramine Look at other dictionaries: methyltryptophan — noun Either of several isomeric methyl derivatives of tryptophan that interfere with signalling in dendritic cells …   Wiktionary Tryptophan 2-C-methyltransferase — In enzymology, a tryptophan 2 C methyltransferase (EC number|2.1.1.106) is an enzyme that catalyzes the chemical reaction:S adenosyl L methionine + L tryptophan ightleftharpoons S adenosyl L homocysteine + L 2 methyltryptophanThus, the two… …   Wikipedia Indolamin-2,3-Dioxygenase — Vorhandene Strukturdaten …   Deutsch Wikipedia Representative poisonous plants — ▪ Table Representative poisonous plants name and distribution toxic principle toxic effects and comments Plants poisonous to eat rosary pea, or jequirity bean (Abrus precatorius); tropical regions abrin (N methyltryptophan) and abric acid onset… …   Universalium DuPhos — ligands DuPhos is a class of asymmetric ligands for asymmetric synthesis. The name DuPhos is derived from the chemical company that developed this type of ligand (DuP, DuPont) and the compound class of phospholanes (Phos) it belongs to. This… …   Wikipedia MRT — magnetic resonance tomography; maximum relaxation time; median range score; median reaction time; median recognition threshold; median relapse time; medical radiation technology/technologist; medical records technician; medical response team;… …   Medical dictionary MRT — • magnetic resonance tomography; • maximum relaxation time; • median range score; • median reaction time; • median recognition threshold; • median relapse time; • medical radiation technology/technologist; • medical records technician; • medical… …   Dictionary of medical acronyms & abbreviations abrine — ˈāˌbrēn, ˈaˌb ;  ̷ ̷ˈ ̷ ̷ noun ( s) Etymology: alteration of abrin : a toxic crystalline amino acid C12H14N2O2 obtained from jequirity; N methyltryptophan distinguished from abrin …   Useful english dictionary 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”