Martin Gruebele

Martin Gruebele
Martin Gruebele
Born January 10, 1964 (1964-01-10) (age 47)
Stuttgart, Germany
Citizenship American
Fields Chemistry, Biophysics, Computational Biology
Institutions University of Illinois at Urbana Champaign
Alma mater University of California, Berkeley California Institute of Technology
Doctoral advisor Richard J. Saykally
Known for Protein folding, scanning tunneling microscopy, Ultrafast laser spectroscopy
Notable awards Sackler Prize, Friedrich Wilhelm Bessel Research Prize, Camille and Henry Dreyfus Foundation Fellowship

Martin Gruebele (Born January 10th, 1964 in Stuttgart, Germany)[1]is a German born American biophysicist and computational biologist who is currently James R. Eiszner Professor of Chemistry, Professor of Physics, Professor of Biophysics and Computational Biology at the University of Illinois at Urbana-Champaign where he is the principal investigator of the 15+ membered Gruebele Group.

Contents

Education

He completed his B.S in Chemistry from the University of California, Berkeley, advised by Ken Sauer (biophysics), Wilhelm Maier (organic synthesis), Richard J. Saykally (laser spectroscopy).He did his graduate work at the University of California, Berkeley in the laboratory of Richard J. Saykally and subsequently held a postdoctoral position with Ahmed Zewail at California Institute of Technology after which he joined the faculty of the University of Illinois in 1992. Dr. Gruebele is also a faculty member of the Beckman Institute and Adjunct Professor of Physics at Michigan State University.

Research

His research is largely concerned with chemical and biological physics ranging from the kinetics of biological systems and quantum dynamics of energy flow within molecules to optically assisted scanning tunneling microscopy.A common theme of his research is the implementation of state-of-the-art laser techniques to interrogate and manipulate complex molecular systems, coupled with quantum or classical simulations leading to better understanding of Protein folding, Molecular vibration, and the switching of energy flow in large molecular structures on surfaces.[2]

Recent pioneering work

  • Tissue-Imaging technique called Nonlinear Interferometric Vibrational Imaging which produces easy-to-read, color-coded images of tissue, outlining clear tumor boundaries, with more than 99 % confidence - in less than five minutes thus leading to much faster biopsy results.[3][4]
  • Fast Relaxation Imaging that combines fluorescence microscopy and fast temperature jumps to study protein dynamics inside the living cells.[5]
  • Nanosecond pressure jump technique that led to 100 times faster Protein folding and could help guide more accurate computer simulations for how complex proteins fold.[6][7]
  • Terahertz Absorption Spectroscopy elucidating for the first time the role of water as a designer fluid that helps proteins change shape.[8][9]
  • Two-state dynamics recorded in glassy Silicon for the first time using high-resolution imaging technology, that confirmed the glass like nature of amorphous silicon until Hydrogen is added.[10][11]


Awards/Honors

Professor Gruebele has received many national and international awards, including Raymond and Beverly Sackler Prize[12] in the Physical Sciences and Friedrich Wilhelm Bessel [13]Prize from von Humboldt Society. He has been awarded A. P. Sloan Fellowship, Camille and Henry Dreyfus Fellowship, and is a Fellow of the American Physical Society & Biophysical Society and a Member of the American Academy of Arts and Sciences.

MEMBERSHIPS/AWARDS:[14]

  • Member, American Academy of Arts and Sciences (USA, 2010)
  • Raymond and Beverly Sackler International Prize (Tel Aviv University, 2008)
  • Member, German Academy of Sciences Leopoldina (2008)
  • James R Eiszner Chair (University of Illinois, 2008)
  • Teaching Excellence Award (School of Chemical Sciences, University of Illinois, 2006)
  • William H and Janet Lycan Professorship (University of Illinois, 2006)
  • Fellow of the Biophysical Society[15] (Biophysical Society, 2005)
  • Friedrich Wilhelm Bessel Research Prize (Alexander von Humboldt Foundation, 2005)
  • Associate of the Center for Advanced Studies (University of Illinois, 2003)
  • Fellow of the American Physical Society (2002)
  • National Science Foundation Creativity Extension Award (2002)
  • Alumni Scholar Professorship (University of Illinois, 2002)
  • Coblentz Award[16] (Coblentz Society, 2000)
  • University Scholar (University of Illinois, 1998)
  • Camille and Henry Dreyfus Teacher-Scholar Award (The Camille and Henry Dreyfus Foundation, 1998)
  • Alfred P Sloan Fellow (Sloan Foundation, 1997)
  • Teaching Excellence Award (School of Chemical Sciences, University of Illinois, 1995)
  • Cottrell Scholar Award (Research Corporation, 1995)
  • Fellow at the Center for Advanced Studies (University of Illinois, 1995)
  • David and Lucile Packard Fellow (Packard Foundation, 1994)
  • National Young Investigator Award (NSF, 1994)
  • List of Teachers Ranked Excellent by their Students (University of Illinois, 1993)
  • O Beckman Award (University of Illinois Research Board, 1992)
  • Dreyfus New Faculty Award (Dreyfus Foundation, 1992)
  • Dow Chemical Graduate Fellow, (Dow Chemical, 1987-1988)
  • IBM Predoctoral Fellow, (IBM, 1986-1987)
  • University Fellow (University of California, Berkeley, 1984-1986)
  • Outstanding Teacher Award (University of California, Berkeley Department of Chemistry, 1985)
  • University Certificate of Distinction (University of California, Berkeley, 1984)
  • Department Citation for Highest Honors (University of California, Berkeley, 1984)

Personal

Dr. Gruebele is married to Nancy Makri[17][18]who is also a Professor of Chemistry at University of Illinois at Urbana-Champaign. He has a keen interest in cycling and has professionally competed in various events.[19][20][21]

Notes

  1. ^ [www.quadrantplastics.com/fileadmin/quadrant/.../gruebele_cv.pdf]
  2. ^ [1]
  3. ^ ”Nonlinear Interferometric Vibrational Imaging Tissue-imaging Technique” , www.imaging-git.com, Nov. 30-2010
  4. ^ “New Tissue-imaging Technique Faster, More Accurate than Biopsies”, www.sott.net, Mon- 29 Nov 2010
  5. ^ ” Scientists observe protein folding in living cells for the first time” , www.scientificamerican.com, February 28-2010
  6. ^ ”Faster protein folding achieved through nanosecond pressure jump “ , www.chemistrytimes.com, 6/3/2009
  7. ^ “Faster protein folding achieved through nanosecond pressure jump”, www.nanotechwire.com, 6/3/2009
  8. ^ ” Water Is 'Designer Fluid' That Helps Proteins Change Shape” , www.sciencedaily.com, Aug. 7-2008
  9. ^ “Water is 'designer fluid' that helps proteins change shape, scientists say”, www.esciencenews.com, August 6-2008
  10. ^ “Researchers record two-state dynamics in glassy silicon” , www.physorg.com, June 14-2011
  11. ^ “Researchers record two-state dynamics in glassy silicon”, www.innovations-report.com,June 15-2011
  12. ^ "Martin Gruebele has been awarded the 2008 Raymond and Beverly Sackler Prize in the Physical Sciences", 11/20/2008
  13. ^ "U. of I. alumni research scholar Martin Gruebele receives Bessel Prize",5/1/2005
  14. ^ “Protein Folding” , www.f1000.com, Retrieved 2011-10-09
  15. ^ "Fellow of the Biophysical Society Award"
  16. ^ [2]
  17. ^ "Gutgsell Endowed Professor: Nancy Makri"
  18. ^ [www.quadrantplastics.com/fileadmin/quadrant/.../gruebele_cv.pdf]
  19. ^ [3]
  20. ^ [4]
  21. ^ [5]

External Links


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • Protein folding — Protein thermodynamics redirects here. For the thermodynamics of reactions catalyzed by proteins, see Enzyme. Protein before and after folding. Protein folding is the process by which a protein structure assumes its functional shape or… …   Wikipedia

  • Folding@home — Original author(s) Vijay Pande Developer(s) Stanford University / Pande lab Initial release 2000 10 01 …   Wikipedia

  • Repliement de protéine — Pour les articles homonymes, voir repliement . Repliement de protéine Le repliement de protéine est le processus physique par lequel un polypeptide se replie dans sa struc …   Wikipédia en Français

  • Repliement de proteine — Repliement de protéine Repliement de protéine Le repliement de protéine est le processus physique par lequel un polypeptide se replie dans sa structure tridimensionnelle caractéristique dans laquelle il est fonctionnel[1] …   Wikipédia en Français

  • Repliement des protéines — Repliement de protéine Repliement de protéine Le repliement de protéine est le processus physique par lequel un polypeptide se replie dans sa structure tridimensionnelle caractéristique dans laquelle il est fonctionnel[1] …   Wikipédia en Français

  • Repliement protéique — Repliement de protéine Repliement de protéine Le repliement de protéine est le processus physique par lequel un polypeptide se replie dans sa structure tridimensionnelle caractéristique dans laquelle il est fonctionnel[1] …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”