- Marc Wilkins (geneticist)
-
Marc R. Wilkins 
Marc R. WilkinsNationality Australia Institutions University of New South Wales Alma mater Macquarie University Doctoral advisor Keith Williams Known for proteome Influences Amos Bairoch Marc R. Wilkins is an Australian scientist who is credited with the concept of the proteome,[1] and is a Professor in the School of Biotechnology and Biomolecular Sciences at the University of New South Wales, Sydney, Australia.
He coined the term proteome in 1994,[2] whilst developing the concept as a PhD student at Macquarie University, Sydney, Australia;[3] this being a generalisation of the concept of the genome to encompass the set of all proteins that can be produced through the genome, through alternative splicing and post-transcriptional modification of messenger RNA.[4][5]
Dr Wilkins held a post-doctoral fellowship from 1995-1997 at the University of Geneva, Switzerland, working with Prof Denis Hochstrasser and Dr Amos Bairoch. He co-developed many of the protein analysis tools available on the ExPASy web server. He subsequently served as a senior post-doctoral fellow in the Australian Proteome Analysis Facility,[6] which was established by the Australian Government in 1995 as the world’s first dedicated proteome research centre.[3]
In 1997 he co-edited the first book on proteomics, Proteome Research: New Frontiers in Functional Genomics (Wilkins et al. (eds), Springer Verlag), which has sold more than 4,000 copies.[6][2]
He was a co-founder, with Dr Jenny Harry,[7] of Australia's largest proteomics company Proteome Systems Ltd. It was established in January 1999, and Dr Wilkins worked there full-time for 6 years as leader of its bioinformatics Research and Development team.[2] It was awarded IBM's "Rookie of the Year Award" for companies in the Asia-Pacific region, in 2003.[6]
Professor Wilkins has been a Chief Investigator or collaborator on various industrial and academic proteomic projects in areas of renal cell carcinoma, gingivitis, tuberculosis, heart failure, exacerbation in cystic fibrosis, antibiotic resistance in B.subtilis, microbial toxin diversity and mad cow disease. Several of these projects remain the subject of ongoing study. He was the Executive Vice President and Head of Bioinformatics at Proteome Systems Inc, now renamed as Tyrian Diagnostics,[8] located in Woburn, Massachusetts and also North Ryde, New South Wales, Australia. His latest research focus is interactome[9] and Systems Biology,[2] is currently a Professor of Systems Biology at the University of New South Wales,[2] and is the director of the Systems Biology Initiative, New South Wales, Australia.[10]
References
- ^ Wilkins, Marc (Dec. 2009). "Proteomics data mining". Expert review of proteomics (England) 6 (6): 599–603. doi:10.1586/epr.09.81. PMID 19929606.
- ^ a b c d e UNSW Staff Bio: Professor Marc Wilkins
- ^ a b "New lab to help Australia’s next crop of eminent scientists", Postgrad and Beyond: Science, Macquarie University. Published 2005. Accessed 18 January 2009.
- ^ Wasinger VC, Cordwell SJ, Cerpa-Poljak A, Yan JX, Gooley AA, Wilkins MR, Duncan MW, Harris R, Williams KL, Humphery-Smith I. (1995). "Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium". Electrophoresis 7 (7): 1090–94. doi:10.1002/elps.11501601185. PMID 7498152.
- ^ Wilkins, MR, Williams, KL, Appel, RD, Hochstrasser, DF, ed (1997). Proteome Research: New Frontiers in Functional Genomics. Springer-Verlag. ISBN 3540627758.
- ^ a b c Macquarie University/CSIRO Internet Innovation Centre Technology Trends Seminar, 2003: Speaker Bio - Marc Wilkins, Published 2003. Accessed 18 January 2009.
- ^ Tyrian Diagnostics: Board Members' Bio Page, Accessed 19 January 2009.
- ^ "New Name for Proteome Systems", Tyrian Diagnostics website press release, published 6 November 2008. Accessed 19 January 2009.
- ^ "Another dimension in protein interaction", Australian Life Scientist, Published September/October 2009. Accessed 1 July 2010.
- ^ Systems Biology Initiative Staff Bio: Professor Marc Wilkins
External links
- UNSW Staff Bio: Professor Marc Wilkins
- The School of Biotechnology and Biomolecular Sciences (Home Page), University of New South Wales
- Carol Ezzell, "Proteins Rule", Scientific American (April 2002).
- The Australian Proteome Analysis Facility (APAF Ltd)
- Tyrian Diagnostics (formerly Proteome Systems Ltd, up to 6 November 2008)
- Systems Biology Initiative Staff Bio: Professor Marc Wilkins
Categories:- Living people
- Australian academics
- American geneticists
- Australian geneticists
- Bioinformaticians
- Macquarie University alumni
- People from Sydney
Wikimedia Foundation. 2010.
