Diflucortolone valerate

Diflucortolone valerate
IUPAC name (6α,11β,16α)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pentanoate
Other names Afusona; Diflucortolone 21-valerate
Identifiers
CAS number	59198-70-8 Y
PubChem	91670
ChemSpider	82773 Y
Jmol-3D images	Image 1
SMILES O=C(OCC(=O)[C@@H]3[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)\C=C\1)[C@@H](F)C[C@H]4[C@@H]2C[C@H]3C)C)C)CCCC
InChI InChI=1S/C27H36F2O5/c1-5-6-7-23(33)34-14-21(31)24-15(2)10-17-18-12-20(28)19-11-16(30)8-9-26(19,4)27(18,29)22(32)13-25(17,24)3/h8-9,11,15,17-18,20,22,24,32H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,22+,24-,25+,26+,27+/m1/s1 Y Key: HHJIUUAMYGBVSD-YTFFSALGSA-N Y InChI=1/C27H36F2O5/c1-5-6-7-23(33)34-14-21(31)24-15(2)10-17-18-12-20(28)19-11-16(30)8-9-26(19,4)27(18,29)22(32)13-25(17,24)3/h8-9,11,15,17-18,20,22,24,32H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,22+,24-,25+,26+,27+/m1/s1 Key: HHJIUUAMYGBVSD-YTFFSALGBY
Properties
Molecular formula	C27H36F2O5
Molar mass	478.57 g mol−1
Melting point	220 °C, 493 K, 428 °F ([1])
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Diflucortolone valerate (also Nerisone cream/oily cream/ointment, Neriderm ointment, Japanese ジフルコルトロン (Jifurucorutoron^?) is a corticosteroid rated Class 2 "potent" (100-150 times) in New Zealand topical steroid system. Chemically, it is a corticosteroid esterified with valeric acid. It is commonly used topically in dermatology. The brand name is Nerisone, its creams come in potencies of 0.1% and 0.3%.

See also

• Diflucortolone

References

1. ^ Chemlink Diflucortolone valerate

This dermatologic drug article is a stub. You can help Wikipedia by expanding it.v · Categories: Corticosteroids Valerates Dermatologic drug stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать курсовую Diflubenzuron Difluorocarbene Look at other dictionaries: diflucortolone valerate — di·flu·cor·to·lone va·ler·ate (di″floo korґtə lōn″) a medium potency synthetic corticosteroid used topically for the relief of inflammation and pruritus in corticosteroid responsive dermatoses …   Medical dictionary Diflucortolone — Clinical data AHFS/Drugs.com Micromedex Detailed Consumer Inf …   Wikipedia Corticosteroid — Corticosterone Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation,… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”