Ciprodex

Ciprodex (ciprofloxacin 0.3% and dexamethasone 0.1%) Sterile Otic Suspension contains the synthetic broad-spectrum antibacterial agent, ciprofloxacin hydrochloride, combined with the anti-inflammatory corticosteroid, dexamethasone, in a sterile, preserved suspension for otic use. Each mL of Ciprodex Otic contains ciprofloxacin hydrochloride (equivalent to 3 mg ciprofloxacin base), 1 mg dexamethasone, and 0.1 mg benzalkonium chloride as a preservative. The inactive ingredients are boric acid, sodium chloride, hydroxyethyl cellulose, tyloxapol, acetic acid, sodium acetate, edetate disodium, and purified water. Sodium hydroxide or hydrochloric acid may be added for adjustment of pH.

Ciprofloxacin, a fluoroquinolone is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid. The empirical formula is C₁₇H₁₈FN₃O₃·HCl·H₂O and the structural formula is:

Dexamethasone, 9-fluoro-11(beta),17,21-trihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione, is an anti-inflammatory corticosteroid. The empirical formula is C₂₂H₂₉FO₅.

This drug is known to be ototoxic and may cause severe side effects.

References

• NIH

This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Drugs Antibiotic stubs Wikimedia Foundation. 2010. Игры ⚽ Нужен реферат? Cipriano Santos Tjipto Mangoenkoesoemo Look at other dictionaries: Ear drop — Ear drops are a form of medicine used to treat or prevent ear infections, especially infections of the outer ear and ear canal (otitis externa). Bacterial infections are sometimes treated with antibiotics. Examples are: Ciprodex ear drops… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”