- OR52D1
-
Olfactory receptor, family 52, subfamily D, member 1 Identifiers Symbols OR52D1; OR11-43 External IDs MGI: 3030480 HomoloGene: 17481 GeneCards: OR52D1 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusSources: Amigo / QuickGO RNA expression pattern 
More reference expression data Orthologs Species Human Mouse Entrez 390066 259058 Ensembl ENSG00000181609 ENSMUSG00000073931 UniProt Q9H346 n/a RefSeq (mRNA) NM_001005163 NM_147056.1 RefSeq (protein) NP_001005163 NP_667267.1 Location (UCSC) Chr 11:
5.51 – 5.51 MbChr 7:
111.25 – 111.26 MbPubMed search [1] [2] Olfactory receptor 52D1 is a protein that in humans is encoded by the OR52D1 gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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See also
References
Further reading
- Bulger M, van Doorninck JH, Saitoh N et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–5134. doi:10.1073/pnas.96.9.5129. PMC 21828. PMID 10220430. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=21828.
- Bulger M, Bender MA, van Doorninck JH et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–14565. doi:10.1073/pnas.97.26.14560. PMC 18958. PMID 11121057. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=18958.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
(tetrapod specific receptors)Family 1Family 2A1 · A2 · A4 · A5 · A7 · A12 · A14 · A25 · A42 · AE1 · AG1 · AG2 · AJ1 · AK2 · AP1 · AT4 · B2 · B3 · B6 · B8 · B11 · C1 · C3 · D2 · D3 · F1 · F2 · G2 · G3 · G6 · H1 · H2 · J1 · J2 · J3 · K2 · L2 · L3 · L5 · L8 · L13 · M2 · M3 · M4 · M5 · M7 · S2 · T1 · T2 · T3 · T4 · T5 · T6 · T8 · T10 · T11 · T12 · T27 · T29 · T33 · T34 · T35 · V1 · V2 · W1 · W3 · W5 · Y1 · Z1
Family 3Family 4Family 5Family 6Family 7Family 8Family 9Family 10Family 11Family 12Family 13Categories:- Human proteins
- Transmembrane receptor stubs
- G protein coupled receptors
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