OR1G1

OR1G1
Olfactory receptor, family 1, subfamily G, member 1
Identifiers
Symbols OR1G1; OR17-130; OR17-209; OR1G2
External IDs MGI3648768 HomoloGene105311 GeneCards: OR1G1 Gene
RNA expression pattern
PBB GE OR1G1 221375 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8390 545417
Ensembl ENSG00000183024 ENSMUSG00000049094
UniProt P47890 n/a
RefSeq (mRNA) NM_003555 XM_001000818
RefSeq (protein) NP_003546 XP_001000818
Location (UCSC) Chr 17:
3.03 – 3.03 Mb
Chr 2:
37.09 – 37.09 Mb
PubMed search [1] [2]

Olfactory receptor 1G1 is a protein that in humans is encoded by the OR1G1 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Contents

See also

References

  1. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K et al. (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet 3 (2): 229–235. doi:10.1093/hmg/3.2.229. PMID 8004088. 
  2. ^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet 18 (3): 243–250. doi:10.1038/ng0398-243. PMID 9500546. 
  3. ^ a b "Entrez Gene: OR1G1 olfactory receptor, family 1, subfamily G, member 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8390. 

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Class II
(tetrapod specific receptors)

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”