OR2AE1

Olfactory receptor, family 2, subfamily AE, member 1
Identifiers
Symbols	OR2AE1; OR2AE2
External IDs	MGI: 3030004 HomoloGene: 79678 GeneCards: OR2AE1 Gene
Gene Ontology Molecular function • receptor activity • olfactory receptor activity Cellular component • plasma membrane • integral to membrane Biological process • sensory perception of smell • response to stimulus Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	81392	258959
Ensembl	ENSG00000244623	ENSMUSG00000062245
UniProt	Q8NHA4	n/a
RefSeq (mRNA)	NM_001005276	NM_146957
RefSeq (protein)	NP_001005276	NP_667168
Location (UCSC)	Chr 7: 99.47 – 99.47 Mb	Chr 16: 19.52 – 19.52 Mb
PubMed search	[1]	[2]

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[1]

See also

• Olfactory receptor

References

1. ^ ^{a b} "Entrez Gene: OR2AE1 olfactory receptor, family 2, subfamily AE, member 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81392. 

Further reading

• "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074. 
• Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster.". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882. 

External links

• MeSH OR2AE1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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