- OR8G2
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Olfactory receptor, family 8, subfamily G, member 2 Identifiers Symbols OR8G2; HSTPCR120; OR8G2P; OR8G4; ORL206; ORL486; TPCR120 External IDs MGI: 3030807 HomoloGene: 115513 GeneCards: OR8G2 Gene Gene Ontology Molecular function • receptor activity
• olfactory receptor activityCellular component • plasma membrane
• integral to membraneBiological process • sensory perception of smell
• response to stimulusRNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 26492 258606 Ensembl n/a ENSMUSG00000060107 UniProt n/a n/a RefSeq (mRNA) NM_001007249 NM_146613.1 RefSeq (protein) NP_001007250 NP_666824.1 Location (UCSC) n/a Chr 9:
39.72 – 39.72 MbPubMed search [1] [2] Olfactory receptor 8G2 is a protein that in humans is encoded by the OR8G2 gene.[1][2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
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See also
References
- ^ Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID 9119360.
- ^ a b "Entrez Gene: OR8G2 olfactory receptor, family 8, subfamily G, member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26492.
Further reading
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=356993.
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
Class II
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- Transmembrane receptor stubs
- G protein coupled receptors
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