OR1A2

OR1A2
Olfactory receptor, family 1, subfamily A, member 2
Identifiers
Symbols OR1A2; MGC119930; MGC119931; OR17-6
External IDs GeneCards: OR1A2 Gene
RNA expression pattern
PBB GE OR1A2 221445 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 26189 n/a
Ensembl ENSG00000172150 n/a
UniProt Q9Y585 n/a
RefSeq (mRNA) NM_012352 n/a
RefSeq (protein) NP_036484 n/a
Location (UCSC) Chr 17:
3.1 – 3.1 Mb
n/a
PubMed search [1] n/a

Olfactory receptor 1A2 is a protein that in humans is encoded by the OR1A2 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

Contents

See also

Notes

  1. ^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. 
  2. ^ a b "Entrez Gene: OR1A2 olfactory receptor, family 1, subfamily A, member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26189. 

References


Further reading

External links

Class II
(tetrapod specific receptors)

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