CHRND

Cholinergic receptor, nicotinic, delta, also known as CHRND, is a human gene.cite web | title = Entrez Gene: CHRND cholinergic receptor, nicotinic, delta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1144| accessdate = ]

PBB_Summary
section_title =
summary_text = The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.cite web | title = Entrez Gene: CHRND cholinergic receptor, nicotinic, delta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1144| accessdate = ]

ee also

* Nicotinic acetylcholine receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Colledge M, Froehner SC |title=Interaction between the nicotinic acetylcholine receptor and Grb2. Implications for signaling at the neuromuscular junction. |journal=Ann. N. Y. Acad. Sci. |volume=841 |issue= |pages= 17–27 |year= 1998 |pmid= 9668219 |doi=
*cite journal | author=Beeson D, Jeremiah S, West LF, "et al." |title=Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17. |journal=Ann. Hum. Genet. |volume=54 |issue= Pt 3 |pages= 199–208 |year= 1990 |pmid= 2221824 |doi=
*cite journal | author=Luther MA, Schoepfer R, Whiting P, "et al." |title=A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671. |journal=J. Neurosci. |volume=9 |issue= 3 |pages= 1082–96 |year= 1989 |pmid= 2564429 |doi=
*cite journal | author=Kreienkamp HJ, Maeda RK, Sine SM, Taylor P |title=Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor. |journal=Neuron |volume=14 |issue= 3 |pages= 635–44 |year= 1995 |pmid= 7695910 |doi=
*cite journal | author=Pasteris NG, Trask BJ, Sheldon S, Gorski JL |title=Discordant phenotype of two overlapping deletions involving the PAX3 gene in chromosome 2q35. |journal=Hum. Mol. Genet. |volume=2 |issue= 7 |pages= 953–9 |year= 1993 |pmid= 8103404 |doi=
*cite journal | author=Engel AG, Ohno K, Milone M, "et al." |title=New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome. |journal=Hum. Mol. Genet. |volume=5 |issue= 9 |pages= 1217–27 |year= 1997 |pmid= 8872460 |doi=
*cite journal | author=Wang ZZ, Hardy SF, Hall ZW |title=Assembly of the nicotinic acetylcholine receptor. The first transmembrane domains of truncated alpha and delta subunits are required for heterodimer formation in vivo. |journal=J. Biol. Chem. |volume=271 |issue= 44 |pages= 27575–84 |year= 1996 |pmid= 8910344 |doi=
*cite journal | author=Brownlow S, Webster R, Croxen R, "et al." |title=Acetylcholine receptor delta subunit mutations underlie a fast-channel myasthenic syndrome and arthrogryposis multiplex congenita. |journal=J. Clin. Invest. |volume=108 |issue= 1 |pages= 125–30 |year= 2001 |pmid= 11435464 |doi=
*cite journal | author=Gomez CM, Maselli RA, Vohra BP, "et al." |title=Novel delta subunit mutation in slow-channel syndrome causes severe weakness by novel mechanisms. |journal=Ann. Neurol. |volume=51 |issue= 1 |pages= 102–12 |year= 2002 |pmid= 11782989 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shen XM, Ohno K, Fukudome T, "et al." |title=Congenital myasthenic syndrome caused by low-expressor fast-channel AChR delta subunit mutation. |journal=Neurology |volume=59 |issue= 12 |pages= 1881–8 |year= 2003 |pmid= 12499478 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466

External links

*

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